Pharmacogenomics in Hypertension

Pharmacogenomics And Hypertension: Current Insights - PMC

In this article, we carried out a comprehensive review of recent findings on the pharmacogenomics of antihypertensive drugs.

Pharmacogenomics of Hypertension Treatment - PubMed

Hypertension is one of the strongest modifiable cardiovascular risk factors, affecting an increasing number of people worldwide.

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo ...

We have carried out a genome‐wide analysis of responses of 4 different antihypertensive drugs using very carefully designed experimental ...

Pharmacogenomics of Hypertension and Preeclampsia - Frontiers

In this perspective article, we present advances of considering the interactions among genetic polymorphisms of different candidate genes within pathways ...

Hypertension pharmacogenomics: in search of personalized ...

This Review summarizes the available literature on the most convincing genetic signals associated with antihypertensive drug responses and adverse ...

The Future of Pharmacogenetics in the Treatment of Hypertension

Pharmacogenetics research has found that multiple genetic variants have a modest influence on individual response to different antihypertensive medications.

Pharmacogenomics of Hypertension Treatment - MDPI

This article reviews the recent pharmacogenomics literature concerning the key classes of antihypertensive drugs currently in use.

A Physiologic Approach to the Pharmacogenomics of Hypertension

This review explores the contribution of genetics to facilitate antihypertensive agent selection and predict treatment efficacy.

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Pharmacogenetics presents as an attractive approach for optimum management of hypertension in Africa.

Pharmacogenomics of Hypertension in CKD: The CKD-PGX Study

We report changes in hypertension control after providing a panel of 11 pharmacogenomic predictors of antihypertensive response.

Advancing management of hypertension through pharmacogenomics

Conceptually, the goal of hypertension pharmacogenomics is to be able to utilize genetic information, along with other pertinent clinical or demographic data, ...

Pharmacogenomics of Hypertension and Heart Disease

While limited clinically translatable data are available for β-blockers or aspirin, sufficient clinically relevant pharmacogenetic data exist ...

Personalized antihypertensive treatment guided by ...

Antihypertensive drugs have long been adopted as the main approaches for reducing BP to physiologically normal levels and preventing ...

PHARMACOGENOMICS OF HYPERTENSION

The aim of this pharmacogenomic (PGX-HT) study is to test the effect of genetic profiles of hydrochlorothiazide (HCTZ) and perindopril (Peri) in patients with ...

Pharmacogenomics of Hypertension Treatment - Semantic Scholar

The results of numerous studies confirm that genotype-based antihypertension therapies are the most effective and may help to avoid the occurrence of major ...

Pharmacogenomic approaches to study the effects of ... - Nature

Until recently, there have been numerous pharmacogenetic/pharmacogenomic studies on antihypertensive drugs using candidate genes, but only a few ...

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy ...

Moreover, uncontrolled HTN has been linked to inter-individual variation in the drugs' response and this has been associated with an ...

Pharmacogenomics considerations in the control of hypertension.

Discussed In Paper More information · Ace Inhibitors, Plain · Angiotensin II Antagonists · Beta Blocking Agents · Calcium channel blockers · diuretics ...

Pharmacogenomics of antihypertensive drugs: Rationale and ...

Conclusions. Pharmacogenetic-guided therapy holds clinical potential for hypertension, but the literature in the field is limited. This trial will add ...

Pharmacogenomics of hypertension in chronic kidney disease

ABSTRACT. Background Patients with chronic kidney disease (CKD) often have uncontrolled hypertension despite polypharmacy. Pharmacogenomic drug- ...