Pharmacogenomics of Hypertension in Africa

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

In Africa, the burden of hypertension has been rising at an alarming rate for the last two decades and is a major cause for cardiovascular ...

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

An insertion/deletion (I/D) variant, rs1799752, in the intron of the ACE gene has been linked to hypertension in studies among Tunisians, Egyptians, and black ...

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Genes implicated in the pharmacogenetics of hypertension were identified in reported African genomic studies (Ta- bles 4 and 5) and are ...

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Document Type: Article ; Subject Terms: *CARDIOVASCULAR disease prevention *PHARMACOGENOMICS *HYPERTENSION *HERBAL medicine *MYOCARDIAL ischemia * ...

Pharmacogenomics of Hypertension Treatment - Semantic Scholar

43 Citations · Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic-Based Approach for the Treatment of Hypertension in Africans.

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo ...

The Genetics of Drug Responsiveness in Essential Hypertension (GENRES) study is a double‐blind, placebo‐controlled cross‐over study where each ...

Genetic Factors Contributing to the Pathogenesis of Essential ...

This study aimed to assess the association of genetic variants and essential hypertension in a cohort of two ethnic South African population groups.

Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic-Based Approach for the Treatment of Hypertension in Africans Available Online.

Hypertension in African Populations: Review and Computational ...

Furthermore, in Africa, there is a paucity of pharmacogenomic data on the treatment of resistant hypertension. Therefore, identification of ...

Genome-wide association study meta-analysis of blood pressure ...

Most hypertension-related genome-wide association studies (GWASs) focus on non-African populations, despite hypertension (a major risk ...

Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure ...

African Americans suffer a higher prevalence of hypertension compared with other racial/ethnic groups. In this study, we performed a ...

African Pharmacogenomics Consortium - Open Research Africa

Coupled with the genetic diversity among Africans, the APC is established to promote pharmacogenomics research and its clinical implementation ...

Pharmacogenomics of Hypertension in CKD: The CKD-PGX Study

Patients with CKD often have uncontrolled hypertension despite polypharmacy. Pharmacogenomic drug-gene interactions (DGIs) may affect the metabolism or efficacy ...

The Future of Pharmacogenetics in the Treatment of Hypertension

The field of HTN pharmacogenomics has generated some conflicting and inconsistent findings with regard to BP response to antihypertensive medication, so it is ...

Hypertensive Pharmacogenomics in African Americans

Hypertensive African Americans demonstrate different responses to antihypertensive medications compared to other ethnic groups and specific ...

Hypertensive Pharmacogenomics in African Americans - Eurekaselect

Hypertensive African Americans demonstrate different responses to antihypertensive medications compared to other ethnic groups and specific candidate gene ...

A Physiologic Approach to the Pharmacogenomics of Hypertension

Hypertension is a multifactorial condition with diverse physiological systems contributing to its pathogenesis. Individuals exhibit significant variation in ...

University of Cape Town Researcher Yields New Data on ... - Gale

University of Cape Town Researcher Yields New Data on Hypertension (Pharmacogenomics of Hypertension in Africa: Paving the Way for a ...

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy ...

Similarly, in Sub-Saharan Africa, HTN is classified as the number one mortality risk with an estimated 500,000 deaths, affecting approximately ...

Pharmacogenomics And Hypertension: Current Insights | PGPM

To address the effects of genetic polymorphisms on blood pressure responses to the antihypertensive drug classes, studies have applied candidate ...