Pharmacotypes across the genomic landscape of pediatric acute ...

Contemporary chemotherapy for childhood acute lymphoblastic leukemia (ALL) is risk-adapted based on clinical features, leukemia genomics and ...

Pharmacotypes across the Genomic Landscape of Pediatric Acute ...

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.

Dive into the research topics of 'Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response'.

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Contemporary chemotherapy for childhood acute lymphoblastic leukemia (ALL) is risk-adapted based on clinical features, leukemia genomics and ...

Pharmacotypes across the genomic landscape of pediatric acute ...

Pharmacology, Toxicology and Pharmaceutical Science · Acute Lymphoblastic Leukemia 100% · Leukemia 50% · Minimal Residual Disease 37% · Clinical Trial 12%.

The genomic landscape of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2754 ...

Pharmacotyping of childhood leukemia provides a blueprint for 'true ...

St. Jude scientists performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic ...

Nature Medicine - X.com

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on... From nature.com · 7:13 PM · Jan 5, 2023.

Pharmacotypes across the Genomic Landscape of Pediatric Acute ...

Pharmacotypes across the Genomic Landscape of Pediatric Acute Lymphoblastic Leukemia and Impact on Treatment Response ... To read the full-text of this research, ...

Pharmacotypes across the genomic landscape of pediatric acute ...

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response ... Authors: Shawn H. R. Lee; Wenjian Yang ...

Pharmacotypes across the genomic landscape of pediatric acute ...

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response · 1 · 2 · 3 · 4.

The genomic landscape of pediatric acute lymphoblastic leukemia ...

Insights into the genomics of ALL further provide compelling biologic rationale to expand the scope of precision medicine therapies for childhood ALL. Herein, ...

The genomic landscape of pediatric acute lymphoblastic leukemia ...

Articles in the Open Access Subset are available under a Creative Commons license. This means they are free to read, and that reuse is permitted ...

Updated genomic landscape for pediatric acute myeloid leukemia ...

Scientists at St. Jude Children's Research Hospital refined and enhanced the classification system for a type of pediatric leukemia using genomic and ...

Toward a Comprehensive One-Stop Shop for Somatic Genomic ...

3. Lee, S.H.R. ∙ Yang, W. ∙ Gocho, Y. ... Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.

Genomic landscape of pediatric B-other acute lymphoblastic ...

Our study shows unbiased European population-based frequencies of novel ALL subtypes, recurrent (cyto)genetic aberrations and their mutual associations.

Pharmacogenomics in Pediatric Oncology Research and Treatment

, et al. Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response . Nat Med.

Pharmacogenomics of childhood leukaemia published

The most comprehensive study yet has described the variations in drug response across different genetic subtypes of acute lymphoblastic ...

Single-cell systems pharmacology identifies development-driven ...

46. Lee, S.H.R. ∙ Yang, W. ∙ Gocho, Y. ... Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.

Pediatric acute lymphoblastic leukemia: where are we going and ...

ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. ,. J Clin Oncol.