Phenotypic and genomic characterization of ST11|K1 CR|hvKP with ...

Phenotypic and genomic characterization of ST11-K1 CR-hvKP with ...

This study investigated the genomic characteristics of seven ST11-K1 CR-hvKP isolates harboring highly homologous KPC-2-encoding multidrug- ...

Characterization of ST11 and ST15 Carbapenem-Resistant ... - NCBI

Map plasmid genome circles were assessed via the Gcview website. Go to: Results. Patient's Clinical Features and CR-hvKP Isolates. Nineteen ...

Phenotypic and Genomic Characterization of Virulence ...

Two unique combinations of virulence-associated genes were detected among hvKp strains. Eleven cases were associated with prmpA2+iucA and two ...

Phenotypic and Genomic Characterization of Virulence ...

mellonella infected with the K1 hyper- virulent Kp isolate was used as reference to define the hypervirulent phenotype. Serum resistance assays of all isolates ...

epidemic ST11 KPC-2-producing strains and non-negligible NDM-5 ...

pneumoniae. Blast analysis showed that pLVKP was present in 50% (15/30) of the genomes with coverage > 50% and identity > 90%. A ...

Understanding carbapenem-resistant hypervirulent Klebsiella ...

CRhvKP ST23 (K1) and ST86 (K2) are the most reported CRhvKP strains produced by this way. The acquisition of CR phenotype by hvKP is associated ...

(PDF) Phenotypic and Genomic Characterization of Virulence ...

... In China, the ST23 clone was common in the hvKp group, and ST11 was the prevalent cKp [1,6,12,13]. ST11 ...

Phenotypic and genetic characterization of hypervirulent Klebsiella ...

Some sequence types (such as ST23, ST65 and ST86) and capsular serotypes (such as K1 and K2) are closely associated with hvKp, especially ST23, ...

Epidemiological characteristics an outbreak of ST11 multidrug ...

ST11 MDR-hvKp derived from hypervirulence and multidrug resistance plasmids not only causes significant treatment difficulties, but also represents an ...

Detection and characterization of putative hypervirulent Klebsiella ...

Recently, genome sequencing revealed potential molecular hvKp marker genes (rmpA, rmpA2, iutA, peg-344, iroB), almost-exclusively located on ...

Characterisation of clinical carbapenem-resistant K1 Klebsiella ...

Highlights · Clinical ST367 K1 K. quasipneumoniae subsp. · Carbapenem-resistant K1 K. quasipneumoniae with pLVPK-like virulence plasmid showed lower virulence and ...

Clinical and genomic characterization of hypervirulent Klebsiella ...

In the New York City study, only 24% (4/17) of hvKp infections were K1-ST23, while 45% (8/17) were K2 without dominant sequence type (Parrott et ...

Severe co-infection caused by difficult-to-diagnose ...

Therefore, these atypical phenotypic characteristics and the presence of hvKp-associated virulence genes may be widespread in the K1-ST82 clone.

Convergence of two serotypes within the epidemic ST11 KPC ...

Whole genome sequencing was performed. The transmission route was reconstructed by combining single nucleotide polymorphisms (SNPs) with the ...

Prevalence of ST11 carbapenem-resistant hypervirulent Klebsiella...

... The recent emergence of ST11 CR-hvKP strains in China has garnered global attention due to the discovery of a pLVPK-like virulence plasmid. This plasmid has ...

pneumoniae ST23 carrying carbapenemase

for an analysis of the population genomics of the hvKp ST23-K1 lineage. However, the time distribution of isolates illustrated above should ...

Deciphering the relative importance of genetic elements in ...

Hypervirulent Klebsiella pneumoniae (hvKp) is a bacterium that can cause serious infections in otherwise healthy individuals. Concern has grown with its ...

Antimicrobial Resistance, Hypervirulent Klebsiella pneumoniae

To date, multiple virulence factors and phenotypes have been well characterized and some of these features serve as a marker for hvKp. Until ...

Adaptive evolution of carbapenem-resistant hypervirulent Klebsiella ...

The epicenter of the CR-hvKp epidemic is Asia, with China bearing a significant burden, and ST11 being the most common sequence type (10, 11).

Hypervirulent Klebsiella pneumoniae - Wiley Online Library

Large genomic analysis of hvKp has ... Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic ...