Phospho|Sulindac

The metabolism and pharmacokinetics of phospho-sulindac (OXT ...

Phospho-sulindac (PS; OXT-328) prevents colon cancer in mice, especially when combined with difluoromethylornithine (DFMO). Here, we explored its metabolism ...

Sulindac: MedlinePlus Drug Information

NSAIDs such as sulindac may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during ...

Sulindac (oral route) - Mayo Clinic

It is best to take this medicine with food. Also drink extra fluids so you will pass more urine while you are using this medicine. This will ...

Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe ...

P-S is a potent inhibitor of colon cancer cell lines (>14-fold more potent than sulindac) and exerts a profound inhibitory effect in preclinical models of colon ...

Sulindac: Uses, Interactions, Mechanism of Action | DrugBank Online

Sulindac is an NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, ...

Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe ...

Keywords: Colon Cancer; Phospho-Sulindac; Sulindac;. Polyamines; Reactive Oxygen Species. Colon cancer, one of the most frequent human ma- lignancies in the ...

Sulindac | Side Effects, Dosage, Uses, and More - Healthline

Sulindac is used to treat pain and redness, swelling, and inflammation from different types of arthritis, ankylosing spondylitis, and short-term shoulder pain.

Sulindac (Clinoril): Uses, Side Effects, Interactions ... - WebMD

Heart Attack and Stroke. Sulindac can increase your risk of a heart attack or stroke that can lead to death. This risk is increased in people ...

Sulindac - Wikipedia

Sulindac ... Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed as Clinoril. Imbaral (not to be confused ...

Sulindac - an overview | ScienceDirect Topics

Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for the treatment of various arthritic conditions and musculoskeletal injuries.

Sulindac, a non-steroidal anti-inflammatory drug, mediates breast ...

Our data showed that sulindac had substantial efficacy as a single agent against 4T1 murine breast cancer and prolonged the survival of tumor-bearing mice.

Clinoril, Sulin (sulindac) dosing, indications, interactions ... - Medscape

150-200 mg PO q12hr. No more than 400 mg. Use lowest effective dose for shortest possible duration. Shoulder Pain 200 mg PO q12hr for 7-14 days.

Sulindac overdose Information | Mount Sinai - New York

Sulindac overdose occurs when someone takes more than the recommended amount of this medicine. People with kidney or liver disease are more likely to develop ...

Sulindac - an overview | ScienceDirect Topics

Sulindac is a nonsteroidal antiinflammatory drug (NSAID) used in the treatment of acute and chronic inflammation.

Definition of sulindac - NCI Dictionary of Cancer Terms

NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

Sulindac Tablets: Uses & Side Effects - Cleveland Clinic

This medication can cause serious ulcers and bleeding in the stomach. It can happen with no warning. Tobacco, alcohol, older age, and poor health can also ...

Eflornithine plus Sulindac for Prevention of Progression in Familial ...

The incidence of disease progression was not significantly lower with the combination of eflornithine and sulindac than with either drug alone.

Association of Sulindac and Erlotinib vs Placebo With Colorectal ...

Treatment with sulindac and erlotinib was associated with a 69% reduction in colorectal polyp burden in patients with FAP.

Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe ...

(1) Compared with sulindac, P-S is much more potent in inhibiting the growth of cultured HCCCs and more efficacious in preventing the growth of ...

Aerosol Administration of Phospho-Sulindac Inhibits Lung ...

Oncogenic Kras was shown to upregulate an Nrf-2–dependent cellular antioxidant program via Raf/MEK/ERK cascade in human lung cancer (47). Hence, the inhibition ...