Platelet|Derived Growth Factor and Arterial Response to Injury

Platelet-Derived Growth Factor and Arterial Response to Injury

The infusion of PDGF-BB after a gentle denudation injury in the rat carotid artery increases intimal thickening but has little effect on intimal ...

Platelet-derived growth factor and arterial response to injury - PubMed

Platelet-derived growth factor and arterial response to injury. Circulation. 1997 Feb 4;95(3):555-6. doi: 10.1161/01.cir.95.3.555. Authors. C E Hart, A W ...

Platelet-Derived Growth Factor and Arterial Response to Injury

Doolittle RF, Hunkapiller MW, Hood LE, DeVare SG, Robbins KC, Aaronson SA, Antoniades HN. Simian sarcoma virus oncogene, v-sis, is derived from ...

The role of alpha and beta platelet-derived growth factor receptor in ...

Carotid arteries were injured by surgical endarterectomy and femoral arteries by balloon catheter dilatation. Immunostaining revealed that both injuries induced ...

An evidence for “response to injury” hypothesis - ScienceDirect.com

Role of platelet-derived growth factor (PDGF) in myointimal thickening described in “response to injury” hypothesis was investigated with artery of rats in ...

Mechanism of Action and In Vivo Role of Platelet-Derived Growth ...

Platelet-derived growth factor stimulation leads to decreased platelet aggregation (66). Human platelets, which are a rich source of PDGF, have PDGF α-receptors ...

PDGF and cardiovascular disease - ScienceDirect.com

Platelet-derived growth factor (PDGF) was identified in a search for serum factors that stimulate smooth muscle cell (SMC) proliferation.

Imbalance between Platelet Vascular Endothelial Growth Factor and ...

One speculative role for VEGF in platelets is promotion of vascular repair and wound healing in conjunction with PDGF. Platelet VEGF and PDGF ...

Endothelial platelet‐derived growth factor‐mediated activation of ...

Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute to the ...

Platelet-derived growth factor and arterial response to injury

; Platelet-derived growth factor and arterial response to injury · Hart, C E ; Clowes, A W · United States: American Heart Association, Inc · Circulation (New York ...

Expression of platelet‑derived growth factor in the vascular walls of ...

PDGF can accumulate at injury sites and proliferate in the extracellular matrix, expanding the area of injury and/or leading to further damage.

The Platelet Response to Tissue Injury - Frontiers

Platelets contain a variety of factors which are essential for the stimulation of angiogenesis, such as VEGF, basic fibroblast growth factor (bFGF), epidermal ...

Factors Controlling Growth of Arterial Cells following Injury

These data suggested that injury and cell death might induce proliferation of cells by release of endogenous mitogen. Basic FGF is present in the arterial wall ...

A Review of Platelet Derived Growth Factor Playing Pivotal Role in ...

PDGF-α specific antibody may promise bright future for wound healing treatment as it can boost chemotaxis and enrich the immune response ...

Platelet-Derived Growth Factor-B (PDGF-B) Induced by Hypoxia ...

Accumulating evidence suggests that platelet-derived growth factor (PDGF) participates in regulating the progression of pulmonary arterial ...

Platelet-derived growth factor: A key regulator of connective tissue ...

5). PDGF and the smooth muscle cell response to vascular injury ... platelet-derived growth factor in arterial smooth muscle cell migration ... collagen in injured ...

Arterial wall response to injury and healing

In summary, strongly held views of arterial injury and repair in which the platelet is the sole purveyor of growth-promoting factors must be modified to include ...

Increased Plasma Levels of Platelet-Derived Growth Factor (PDGF ...

Abstract. Platelet-derived growth factor (PDGF) could play a role in both vascular hypertrophy and atherosclerotic disease associated with hypertension. To.

Glyceollins inhibit platelet-derived growth factor-mediated human ...

Platelet-derived growth factor (PDGF)-BB can induce abnormal proliferation and migration of vascular smooth muscle cells (VSMC) that are involved in the ...

Selective Tyrosine Kinase Inhibitor for the Platelet-Derived Growth ...

In the neointima, after repeated injury, upregulation of PDGF-AA was seen to coincide with a prompt proliferative response of smooth muscle cells (SMC).