Platelet|derived growth factor β receptor regulates interstitial ...

Platelet-derived growth factor beta receptor regulates interstitial fluid ...

Platelet-derived growth factor (PDGF) isoforms lead to mitogenic, survival, and chemotactic responses in a variety of mesenchymal cell types ...

Platelet-derived growth factor β receptor regulates interstitial fluid ...

The PDGF-β Receptor/PI3K Pathway Plays a Role in Fluid Pressure Homeostasis of Loose Connective Tissue. In vivo, extracellular matrices serve to ...

Platelet-derived growth factor β receptor regulates interstitial ... - PNAS

Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling. Rainer Heuchel, Ansgar ...

Platelet Derived Growth Factor B - an overview | ScienceDirect Topics

Osteoblast expression of PDGF and VEGF is regulated by other locally derived growth factors. ... PDGF-B and platelet-derived growth factor β receptor (PDGFR-β) ...

Platelet Derived Growth Factor B - an overview | ScienceDirect Topics

PDGF is produced by the epithelium and interacts with PDGF receptors (PDGFRs) on interstitial mesenchymal cells. ... beta isoforms may also cross-regulate the ...

Mechanism of Action and In Vivo Role of Platelet-Derived Growth ...

Also, the mouse β-receptor promoter has been isolated (24); nuclear factor Y was found to control its basal transcription activity (209). E. Activation of PDGF ...

PDGF receptors as cancer drug targets - Cell Press

21. Heuchel, R ∙ Berg, A ∙ Tallquist, M ... Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3.

Involvement of platelet‐derived growth factor ligands and receptors ...

The PDGF isoforms act on their target cells via binding to structurally similar α- and β-tyrosine kinase receptors (PDGFRα and PDGFRβ, ...

Expression of platelet-derived growth factor and its receptors in the ...

Its receptor, PDGFRα, is expressed by interstitial cells. PDGF B-chain transcripts are most highly expressed by vascular endothelial cells of developing and ...

Platelet-Derived Growth Factor Production by B16 Melanoma Cells ...

Heuchel R, Berg A, Tallquist M, et al Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase ...

Platelet-Derived Growth Factor BB–Mediated Normalization of ...

Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling. Proc ...

The platelet-derived growth factor receptor as a therapeutic target

Heuchel R, Berg A, Tallquist M, et al.: Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through ...

PDGF receptors as cancer drug targets - Cell Press

Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phos- phatidylinositol-3′ kinase signaling. Proc. Natl. Acad. Sci ...

Role of platelet-derived growth factors in physiology and medicine

Diffusion of PDGF in the tissue interstitium is regulated by binding to ex- tracellular matrix components (Fig. 3). For PDGF-A and. PDGF-B, such binding is ...

Roles of PDGF in animal development

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling. Proc.

B Monoclonal Antibody, MOR8457, Reveals Conformational ...

Platelet derived growth factor-BB (PDGF-BB) is an important mitogen and cell survival factor during development. PDGF-BB binds PDGF receptor-β (PDGFRβ) to ...

Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR ...

PDGF is a 30 kDa dimer composed of an A- and/or B-chain, which are encoded by separate genes and regulated independently. Two additional genes were identified ...

Role of Platelet-Derived Growth Factors in the Testis

Cells expressing PDGFR-β progressively appear in the interstitial ... Platelet-derived growth factor receptor β-subtype regulates proliferation and migration of ...

Platelet-derived growth factor 13 receptor regulates interstitial - jstor

kinase receptors, PDGF-a receptor and ,B receptor (1).The. PDGF signal transduction machinery has been analyzed ex- tensively for the PDGF-03 receptor (for ...

Antagonism of Platelet-Derived Growth Factor Receptor in Non ...

... β stimulation reversed interstitial hypotension induced by dextran (17). ... regulated by PDGF-B and VEGF. Development. 1998. ;. 125. : 1591. –8 ...