Platelet Proteomes

The Platelet Proteome - PMC - PubMed Central

Over 1100 platelet proteins have been identified using proteomic techniques. Various subproteomes have been characterized, including platelet releasates (the “ ...

Assessment of a complete and classified platelet proteome ... - Nature

Novel platelet and megakaryocyte transcriptome analysis allows prediction of the full or theoretical proteome of a representative human ...

The first comprehensive and quantitative analysis of human platelet ...

We calculate a total of ∼ 20 million protein molecules per platelet, corresponding to 1.5 mg of protein/109 platelets which fits well to common laboratory ...

Platelet Proteomes, Pathways, and Phenotypes as Informants of ...

Highlights. •. Platelets serve essential roles in hemostasis to prevent bleeding, but also contribute to inflammatory responses and disease ...

Analysis of the Healthy Platelet Proteome Identifies a New Form of ...

O-Glycosylation was detected as a dominant modification of the secreted proteins. A new form of domain-specific O-fucosylation was detected on the protein MMRN ...

The Platelet Proteome - ScienceDirect.com

The highly dynamic protein content of platelets has been studied by diverse proteomic technologies using resting and activated platelets, and in both health ...

Proteomics: A Tool to Study Platelet Function - MDPI

This review focuses on the role of proteomics in understanding the molecular basics of the classical and newly emerging functions of platelets.

What Can Proteomics Tell Us About Platelets? | Circulation Research

Platelet proteomics will represent an invaluable tool for characterizing the fundamental processes that affect platelet homeostasis.

Full article: How can we use proteomics to learn more about platelets?

Studies of platelet proteomes in conditions such as heart failure, cancer, myocardial infarction, and COVID-19, all note proteomic changes in ...

Platelet proteome reveals features of cell death, antiviral response ...

Platelets play a significant role in COVID-19 pathogenesis via platelet activation, antiviral response, and disease severity.

Platelet proteomic profiling reveals potential mediators of ...

Platelet proteomic profiling reveals potential mediators of immunothrombosis and proteostasis in myeloproliferative neoplasms.

The Perspectives of Platelet Proteomics in Health and Disease - MDPI

In this review, we explored the potential of accurate platelet proteomic research, which is required to identify novel diagnostic and pharmaceutical targets.

Platelet proteomics - Zufferey - 2012 - Mass Spectrometry Reviews

They showed that the strength of the agonist influences the amount of secreted proteins and the secretion profile, and that aspirin decreases ...

Platelet proteomics in cardiovascular diseases - ScienceDirect.com

Platelet proteomics can be applied to cardiovascular research to search for novel platelet biomarkers and drug targets.

Platelet proteomics - Journal of Thrombosis and Haemostasis

In contrast, proteomics, the study of the protein complement of a genome, will have a major impact on platelet biology. It offers the opportunity to ...

Platelet Proteomics - CiMUS - USC

We are focusing our studies on healthy and diseased platelets in order to identify novel biomarkers and drug targets that may help to treat / diagnose those ...

What can the plasma proteome tell us about platelets (and vice ...

The plasma proteome can mirror the platelet proteome, and hence play an important role in elucidating both physiologic and pathologic processes.

Platelet proteomics - Journal of Thrombosis and Haemostasis

We briefly describe various proteomic approaches to unravel platelet biology, including the documentation of platelet proteins, the investigation of thrombin- ...

The Platelet Microparticle Proteome - ACS Publications

This report details the first proteomic data set from microparticles generated from platelets. We have identified 578 proteins, 380 of which have not been ...

The Platelet Web - Systems Biology Workbench

The database was established combining data from recent platelet proteome and transcriptome (SAGE) studies with information on protein-protein interactions ...