- Polygenic Risk Score Improves Prediction of Primary Open Angle ...🔍
- The Clinical Usefulness of a Glaucoma Polygenic Risk Score in 4 ...🔍
- Polygenic Risk Scores for POAG in Populations of African Descent🔍
- Polygenic Risk Score Enhances Prediction of Glaucoma Onset🔍
- Polygenic Risk Scores Driving Clinical Change in Glaucoma🔍
- Polygenic Risk Score Identifies Individuals at Higher Risk of POAG🔍
- Polygenic Risk Score Is Associated With Intraocular Pressure and ...🔍
- Polygenic Risk Scores for Glaucoma Onset in the Ocular ...🔍
Polygenic Risk Score Improves Prediction of Primary Open Angle ...
Polygenic Risk Score Improves Prediction of Primary Open Angle ...
Polygenic risks score (PRS) offers a measure of aggregate genetic burden. In this study, we assess whether PRS improves risk stratification in patients with ...
Polygenic Risk Score Improves Prediction of Primary Open Angle ...
Higher PRS is associated with increased risk for, and earlier development of POAG in patients with ocular hypertension.
The Clinical Usefulness of a Glaucoma Polygenic Risk Score in 4 ...
We used a polygenic risk score (PRS) to identify high-risk groups for primary open-angle glaucoma (POAG) within population-based cohorts.
Polygenic Risk Scores for POAG in Populations of African Descent
This cross-sectional study investigates how published polygenic risk scores for primary open-angle glaucoma (POAG) perform in groups with ...
Polygenic Risk Score Enhances Prediction of Glaucoma Onset
A higher polygenic risk score (PRS) was associated with an increased risk for earlier development of primary open-angle glaucoma (POAG) ...
Polygenic Risk Scores Driving Clinical Change in Glaucoma
... improve risk prediction for primary open-angle glaucoma. . Nat ... An intraocular pressure polygenic risk score stratifies multiple primary open- ...
Polygenic Risk Score Identifies Individuals at Higher Risk of POAG
A polygenic risk score (PRS) was able to identify individuals who had the highest risk of primary open-angle glaucoma (POAG) in a study aimed at finding the ...
Polygenic Risk Score Improves Prediction of Primary Open Angle ...
Polygenic Risk Score Improves Prediction of Primary Open Angle Glaucoma Onset in the Ocular Hypertension Treatment Study. Singh, Rishabh K; Zhao, Yan; Elze, ...
Polygenic Risk Score Improves Prediction of Primary Open Angle ...
Primary open-angle glaucoma (POAG) is a highly heritable disease with 127 identified risk loci. Polygenic risks score (PRS) offers a measure of aggregate ...
Polygenic Risk Score Is Associated With Intraocular Pressure and ...
The weighted PRS improved the discriminatory power for POAG (AUC increased by 5%, P = 6.2 × 10−22) when added to the other covariates. The unweighted PRS ...
(PDF) Polygenic Risk Score Improves Prediction of Primary Open ...
Objective or Purpose Primary open-angle glaucoma (POAG) is a highly heritable disease with 127 identified risk loci. Polygenic risks score (PRS) offers a ...
Polygenic Risk Scores for Glaucoma Onset in the Ocular ...
Importance: Primary open-angle glaucoma (POAG) is ... improve patient risk ... Prediction models significantly improved with the addition of PRS as a covariate (C ...
Diversity in Polygenic Risk of Primary Open-Angle Glaucoma - MDPI
Prioritizing diversity in the discovery of risk variants will improve the performance and utility of GRS and PRS-derived risk estimation for ...
Polygenic risk score linked with higher risk for POAG in patients with ...
An increase in polygenic risk score is associated with earlier development of primary open-angle glaucoma. The findings may help with shared ...
Polygenic Risk Scores for Glaucoma Onset in the Ocular ...
IMPORTANCE: Primary open-angle glaucoma (POAG) is a highly heritable disease, with 127 identified risk loci to date. Polygenic risk score ...
Polygenic Risk Scores and Genetically Complex Eye Disease
The success of genome-wide association studies (GWASs) in uncovering genetic variants associated with complex eye diseases has paved the way ...
Higher Polygenic Risk Score Tied to Increased Risk for Glaucoma
Higher polygenic risk score (PRS) was associated with an increased risk for primary open-angle glaucoma (POAG) in patients with ocular hypertension.
Retinal nerve fiber layer polygenic risk score is associated ... - IOVS
Our study aimed to construct and validate a polygenic risk score (PRS) for RNFL thickness, using the UK Biobank (UKB) cohort, to assess its association with ...
Increased Risk of POAG Associated With Polygenic Risk Score
Polygenic risk score was found to be associated with a higher risk of primary open angle glaucoma (POAG) in patients with ocular ...
[PDF] An Intraocular Pressure Polygenic Risk Score Stratifies ...
Polygenic Risk Score Improves Prediction of Primary Open Angle Glaucoma Onset in the Ocular Hypertension Treatment Study · Rishabh K SinghYan Zhao +9 authors