Polygenic Scores for Cognitive Abilities and their Association with ...

Polygenic Scores for Cognitive Abilities and Their Association with ...

Intelligence is a highly polygenic trait and genome-wide association studies (GWAS) have identified thousands of DNA variants contributing with small ...

Polygenic Scores for Cognitive Abilities and Their Association with ...

We used deep-phenotyping to investigate the molecular determinants of individual differences in cognitive ability.

Polygenic Scores for Cognitive Abilities and their Association with ...

EA-PGS and IQ-PGS had the highest incremental R2 for crystallized intelligence (4.17%; 3.16%) and the weakest for short-term memory (1.11%; 0.30 ...

(PDF) Polygenic Scores for Cognitive Abilities and Their Association ...

IQ-PGS, CP-PGS, and EA-PGS had the highest incremental R²s for general (2.71%; 4.27%; 2.06%), verbal (3.30%; 4.64%; 1.61%), and numerical ...

[PDF] Polygenic Scores for Cognitive Abilities and Their Association ...

The results indicate that PGS derived from light-phenotyping GWAS do not reflect different facets of intelligence equally well, and thus should not be ...

Polygenic Scores for Cognitive Abilities and their Association with ...

POLYGENIC CORRELATES OF GENERAL INTELLIGENCE. 1. Polygenic Scores for Cognitive Abilities and their Association with Different Aspects of ...

Multi-polygenic score prediction of mathematics, reading ... - Nature

Specific cognitive abilities (SCA) correlate genetically about 0.50, which underpins general cognitive ability (g), but it also means that there

A longitudinal study of polygenic score and cognitive function ...

The current polygenic scores (PGSs) combining millions of variants across the genome can identify AD cases with high accuracy, with area under ...

Association of Cognitive Polygenic Index and Cognitive ... - MDPI

Genome-wide association studies have discovered common genetic variants associated with cognitive performance. Polygenic scores that ...

Polygenic Scores for Cognitive Abilities and Their Association with ...

Supporting: 4, Mentioning: 16 - Intelligence is a highly polygenic trait and genome-wide association studies (GWAS) have identified thousands of DNA ...

0142 Polygenic scores for longevity and cognitive performance are ...

Higher polygenic score for longevity was associated with lower biological brain age in men (β = -0.24; SD = 0.10; p = 0.02), and higher polygenic score for ...

Childhood Socioeconomic Status and Polygenic Scores for ...

Previous investigations conducted in small samples have suggested that SES is linked with cognitive ability independent of polygenic prediction ...

Polygenic predictors of age-related decline in cognitive ability - Nature

Polygenic scores can be used to distil the knowledge gained in genome-wide association studies for prediction of health, lifestyle, ...

Polygenic influences associated with adolescent cognitive skills

We show that polygenic risk scores for educational attainment, intelligence, and cognitive performance explained up to 10% of the variance in academic skills.

Intelligence Polygenic Score Is More Predictive of Crystallized ...

We found that polygenic predictors of intelligence test performance (based on genome-wide association meta-analyses of data from 269,867 ...

Investigating the Association Between Polygenic Risk Scores for ...

A PRS is a method to predict the genetic susceptibility of an individual to a specific disease by its summarized genetic risk for the disease ...

Polygenic risk of ischemic stroke is associated with cognitive ability

In LBC1936, 7 of 120 correlations between cognitive test scores and polygenic risk scores for ischemic stroke (and its subtypes) reached a significance level of ...

Association between polygenic score and cognitive ability. The ...

Association between polygenic score and cognitive ability. The plotted points in (a) show the magnitude of the effect of a 1-SD increase in polygenic score ...

Polygenic Scores for Cognitive Abilities and their Association with ...

Polygenic scores (PGS) can aggregate those effects for trait prediction in independent samples. As large-scale light-phenotyping GWAS operationalized ...

Cognitive Capacity Genome-Wide Polygenic Scores Identify ... - MDPI

The top cognitive capacity GPS-phenotype associations are presented from the full PheWAS results (available in Supplementary Table S1). Positive β (effect size) ...