Polygenic Susceptibility to Hypertension and Blood ...

Polygenic Susceptibility to Hypertension and Blood ... - PubMed

A higher PSH is associated with worse BP control in stroke survivors. These findings point to genetic predisposition as an important ...

Polygenic Susceptibility to Hypertension and Blood Pressure ...

Blood pressure (BP) is often not at goal in stroke survivors, leaving individuals vulnerable to additional vascular events.

Polygenic risk scores associate with blood pressure traits across the ...

Polygenic risk scores associate with blood pressure traits across the lifespan. Karsten Øvretveit, Karsten Øvretveit KG Jebsen Centre for Genetic Epidemiology.

Polygenic Susceptibility to Hypertension is Associated with ...

Blood pressure is a highly heritable trait with numerous related genetic risk variants identified. While prior studies showed that PSH is associated with ...

Polygenic Risk Scores Predict Hypertension Onset and ...

Compared with having a 20 to 80 percentile range polygenic risk score, a polygenic risk score in the highest 2.5% conferred 2.3-fold risk of ...

Study uncovers the role of polygenic risk scores in hypertension ...

The genetic predisposition to hypertension was quantified using a previously validated systolic blood pressure polygenic risk score. The ...

Utility of a Systolic Blood Pressure Polygenic Risk Score With ...

A high PRS for SBP was associated with a reduced blood pressure response to chlorthalidone and may be a useful metric to personalize treatment choices.

Polygenic Resistance to Blood Pressure Treatment and Stroke Risk ...

Conclusions: Among participants on antihypertensive medication, increased genetic predisposition to hypertension correlates with higher risk of ...

Polygenic risk score for blood pressure and lifestyle factors with ...

This prospective study aimed to examine the associations of blood pressure PRS with all-cause and CVD mortality and to quantify the attributable risk by ...

Polygenic predisposition to hypertension predicts blood pressure ...

There has been a lot of research about polygenic risk for, let's say, hypertension and the clinical outcomes. So we know that polygenic ...

Blood pressure polygenic risk scores tackle hard endpoints - Nature

BP traits are highly polygenic, with 2103 independent signals identified in the latest large-scale genome-wide association study for systolic ( ...

Blood Pressure Polygenic Risk Score Associated with ...

A polygenic risk score aggregates the risk associated with many common DNA sequence variants into a single factor. The current study examined a ...

Polygenic Interactions With Environmental Exposures in Blood ...

What Are the Clinical Implications? ... Several modifiable risk factors for hypertension may have differential effects on phenotypic expression ...

Polygenic Susceptibility to Hypertension is Associated with Worse ...

Polygenic Susceptibility to Hypertension is Associated with Worse Cognitive Performance in Middle-Aged Persons without Dementia · Find this ...

Polygenic susceptibility to hypertension and cognitive performance ...

Background and Objectives: Mounting evidence indicates that hypertension leads to a higher risk of dementia. Hypertension is a highly heritable trait, ...

Hypertension: How genes may help predict high blood pressure risk

By using polygenic risk scores, scientists said they found that study participants with the highest genetic risk for hypertension have mean ...

BP Polygenic Risk Scores May Complement Measured BP for CVD ...

In a large cohort of U.K. women, genetic predisposition to high blood pressure and higher body mass index was significantly associated with ...

Polygenic Susceptibility to Hypertension and Blood Pressure ...

Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. uri icon. Overview; Identity; Additional Document Info; View All.

Scientists discover over 100 new genomic regions linked to blood ...

From these analyses, the researchers were able to calculate a polygenic risk score, which combines the effects of all genomic variants together ...

Associations of polygenic risk scores for preeclampsia and blood ...

BP-PRS is strongly associated with hypertensive disorders of pregnancy. Our current observations suggest that the BP-PRS could capture the genetic architecture ...