Polygenic Susceptibility to Hypertension and Blood Pressure ...

Polygenic Susceptibility to Hypertension and Blood ... - PubMed

A higher PSH is associated with worse BP control in stroke survivors. These findings point to genetic predisposition as an important ...

Blood pressure (BP) is often not at goal in stroke survivors, leaving individuals vulnerable to additional vascular events. Given that BP is a highly ...

Polygenic Susceptibility to Hypertension is Associated with ...

Blood pressure is a highly heritable trait with numerous related genetic risk variants identified. While prior studies showed that PSH is associated with ...

Polygenic risk scores associate with blood pressure traits across the ...

Blood pressure (BP) traits have a strong genetic component that can be quantified with polygenic risk scores (PRSs). To date, the performance of ...

Polygenic Risk Scores Predict Hypertension Onset and ...

Compared with having a 20 to 80 percentile range polygenic risk score, a polygenic risk score in the highest 2.5% conferred 2.3-fold risk of ...

Utility of a Systolic Blood Pressure Polygenic Risk Score With ...

Elevated blood pressure (BP) is determined by a complex interplay between life-course exposures and genetics, and studies of HTN estimate ...

Polygenic Resistance to Blood Pressure Treatment and Stroke Risk ...

Common genetic variation explains up to 40% of inter-individual BP variability. Despite this compelling physiological impact, its role in BP ...

Study uncovers the role of polygenic risk scores in hypertension ...

The genetic predisposition to hypertension was quantified using a previously validated systolic blood pressure polygenic risk score. The ...

Blood pressure polygenic risk scores tackle hard endpoints - Nature

Polygenic risk scores (PRS) are currently the most informative way of quantifying genetic burden for BP traits and hypertension.

Polygenic Interactions With Environmental Exposures in Blood ...

Additionally, polygenic risk scores for BP traits are associated with clinically significant phenotypic variation. However, interactions between ...

Polygenic predisposition to hypertension predicts blood pressure ...

There has been a lot of research about polygenic risk for, let's say, hypertension and the clinical outcomes. So we know that polygenic ...

Evaluating the use of blood pressure polygenic risk scores across ...

Based on such GWAS, Polygenic Risk Scores (PRSs) have been constructed for both hypertension and BP phenotypes. These BP PRSs are associated ...

Hypertension: How genes may help predict high blood pressure risk

“Blood pressure is a highly polygenic trait, meaning that it is influenced by thousands of different genetic variants, and each of these genetic ...

BP Polygenic Risk Scores May Complement Measured BP for CVD ...

In a large cohort of U.K. women, genetic predisposition to high blood pressure and higher body mass index was significantly associated with ...

Utility of a Systolic Blood Pressure Polygenic Risk Score With ...

This genetic association study uses data from Black participants in the the Genetics of Hypertension Associated Treatments (GenHAT) study to ...

Blood Pressure Polygenic Risk Score Associated with ...

This study shows that a polygenic risk score was associated with blood pressure traits and cardiovascular risk.

Polygenic Susceptibility to Hypertension is Associated with Worse ...

Polygenic Susceptibility to Hypertension is Associated with Worse Cognitive Performance in Middle-Aged Persons without Dementia · Find this ...

Polygenic Susceptibility to Hypertension and Blood Pressure ...

Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. uri icon. Overview; Identity; Additional Document Info; View All.

Scientists discover over 100 new genomic regions linked to blood ...

From these analyses, the researchers were able to calculate a polygenic risk score, which combines the effects of all genomic variants together ...

Polygenic susceptibility to hypertension and cognitive performance ...

... high (≥80th percentile) PSH according to results of 2 polygenic risk scores for systolic and diastolic blood pressure (BP) generated with data on 732 genetic ...