Polygenic architecture of brain structure and function

Polygenic architecture of brain structure and function, behaviors ...

This study delivers a comprehensive map of the relationships between genetic profiles, neuroanatomical diversity, and the spectrum of cognitive and behavioral ...

Exploring the genetic architecture of brain structure and ADHD using ...

Careful consideration of the polygenicity and complex genetic architecture could aid in the understanding of the underlying brain mechanisms. We ...

Brain Structure and Function Show Distinct Relations With Genetic ...

The polygenic nature poses a challenge to understanding the genetic architecture and biological mechanisms underlying specific traits (4). A promising approach ...

Structural architecture and brain network efficiency link polygenic ...

In addition, PGS can be leveraged to map the pathway from genetic disposition to phenotype. Whereas it is known that intelligence is influenced ...

Structural architecture and brain network efficiency link polygenic ...

... brain structure and function mediate this relationship. Here, we show that individuals with higher PGS for educational attainment and intelligence had ...

Polygenic risk scores and brain structures both contribute to ...

Brain structure, in turn, is also influenced by genetics. Here, we investigated the association of genetic and brain structural variation with externalizing ...

The genetic architecture of human brainstem structures and their ...

Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain ...

bioRxiv on X: "Polygenic architecture of brain structure and function ...

Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children https://t.co/z81msvxs7u #bioRxiv.

Insights Into the Shared Genetic Architecture of Subcortical Brain ...

Overall, these results provide additional evidence for the heritable and highly polygenic architecture of subcortical brain structure, and highlight known and ...

Polygenic Risk for Schizophrenia, Brain Structure, and ...

Genome-wide association studies (GWAS) have identified hundreds of significant loci and indicate a polygenic architecture of schizophrenia.8,10, ...

Exploring the genetic architecture of brain structure and ADHD using ...

Request PDF | Exploring the genetic architecture of brain structure and ADHD using polygenic neuroimaging-derived scores | Genome‐wide association studies ...

Genetic architecture of brain age and its causal relations ... - Nature

These results emphasize the polygenic architecture of brain age ... Methionine adenosyltransferase: Structure and function. Pharmacol ...

Brain structure and function show distinct relations with genetic ...

This polygenic nature poses a challenge to understanding the genetic architecture and biological mechanisms underlying specific traits. A ...

Genetic architecture of the white matter connectome of the human ...

Multivariate associations between structural connectivity and polygenic dispositions to brain-related disorders or behavioral traits were also ...

Polygenic Architecture of Human Neuroanatomical Diversity

Our results confirm the polygenic architecture of neuroanatomical diversity, with SNPs capturing from 40% to 54% of regional brain volume variance.

Structural architecture and brain network efficiency links polygenic ...

Structural architecture and brain network efficiency links polygenic scores to intelligence ... To read the file of this research, you can request a copy directly ...

Brain imaging genomics: influences of genomic variability on the ...

Such systematic genomic screens of millions of genetic variants have generated initial insights into the genetic architecture of brain ...

Polygenic scores for handedness and their association with ...

... structure–function relationships for this brain area in more detail. ... architecture of structural left-right asymmetry of the human brain.

Polygenic architecture of brain structure and function, behaviors ...

The human brain undergoes structural and functional changes during childhood, a critical period in cognitive and behavioral development. Understanding the ...

Polygenic Architecture of Human Neuroanatomical Diversity

obtained using structural and functional MRI could provide an alternative source of mechanistic insight. The brain imaging literature is rich in ...