Polygenic risk scores associate with blood pressure traits across the ...

Genetic risk factors are associated with BP traits across the lifespan, beginning in the first years of life. Given the importance of ...

Polygenic risk scores associate with blood pressure traits across the lifespan. Karsten Øvretveit, Karsten Øvretveit KG Jebsen Centre for Genetic Epidemiology.

Polygenic risk scores associate with blood pressure traits across the ...

Blood pressure (BP) traits have a strong genetic component that can be quantified with polygenic risk scores (PRSs). To date, the performance of BP PRSs has ...

Evaluating the use of blood pressure polygenic risk scores across ...

We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population ...

Blood Pressure Polygenic Risk Score Associated with ...

This study shows that a polygenic risk score was associated with blood pressure traits and cardiovascular risk. Moreover, the polygenic risk ...

Polygenic Risk Scores Predict Hypertension Onset and ...

Systolic and diastolic blood pressure polygenic risk scores improved clinical risk prediction of hypertension, increasing the C statistics by ...

Blood pressure polygenic risk scores tackle hard endpoints - Nature

Polygenic risk scores (PRS) are currently the most informative way of quantifying genetic burden for BP traits and hypertension.

Genome-wide analysis in over 1 million individuals of European ...

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Polygenic risk scores associate with blood pressure traits across the ...

Blood pressure (BP) traits have a strong genetic component that can be quantified with polygenic risk scores (PRSs). To date, the performance of ...

Polygenic Risk Scores Predict Hypertension Onset ... - AHA Journals

... hypertension onset estimates across blood pressure polygenic risk score ... over 1 million people identifies 535 new loci associated with blood pressure traits.

Polygenic risk scores associate with blood pressure traits ... - OUCI

Polygenic risk scores associate with blood pressure traits across the lifespan ... Authors: Karsten Øvretveit; Emma M L Ingeström; Michail Spitieris; Vinicius ...

Evaluating polygenic risk scores for predicting cardiometabolic traits ...

Using publicly available, large-scale genome-wide association studies summary statistics, we constructed cross-ethnic PRSs for T2D, hypertension, body mass ...

Polygenic risk scores associate with blood pressure traits across the ...

Aims Hypertension is a major modifiable cause of morbidity and mortality that affects over 1 billion people worldwide. Blood pressure (BP) traits have a ...

A multi-ethnic polygenic risk score is associated with hypertension ...

Polygenic risk scores have potential to predict an individual's risk of disease based on genetic markers. Here, the authors develop a polygenic ...

Polygenic risk scores associate with blood pressure traits across the ...

Dive into the research topics of 'Polygenic risk scores associate with blood pressure traits across the lifespan'. Together they form a unique fingerprint.

phenome-wide analysis of a blood pressure polygenic risk score

Objective: Blood pressure (BP) is a polygenic trait with > 1400 known single nucleotide polymorphisms (SNPs), and BP polygenic risk scores (PRSs) strongly ...

(PDF) Evaluating the use of blood pressure polygenic risk scores ...

PDF | We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We.

Life-Course Associations between Blood Pressure-Related ... - MDPI

The multi-ancestry genome-wide polygenic risk scores (PRSs) for systolic BP (SBP), diastolic BP (DBP), and hypertension were tested for an association with ...

Polygenic risk scores associate with blood pressure traits across the ...

Early-onset hypertension: < 55 years old; late-onset hypertension: ≥ 55 years old. Hazard ratios (with 95% CIs) for low genetic risk (1st PRS decile) and high ...

Evaluating the use of blood pressure polygenic risk scores across ...

Kurniansyah, N. et al. A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nat. Commun. 13, ...