Polygenic susceptibility to hypertension is associated with worse ...

Polygenic Susceptibility to Hypertension and Cognitive Performance ...

... associated with worse cognitive performance. These findings suggest that genetic predisposition to hypertension influences brain health in ...

These findings provide evidence for a causal link between SBP and DBP and worse cognitive functioning.

Polygenic Susceptibility to Hypertension and Blood ... - PubMed

A higher PSH is associated with worse BP control in stroke survivors. These findings point to genetic predisposition as an important ...

Polygenic Susceptibility to Hypertension is Associated with Worse ...

Hypertension is a highly heritable trait and a higher polygenic susceptibility to hypertension (PSH) is known to be associated with higher risk ...

Polygenic Susceptibility to Hypertension is Associated with Worse ...

Polygenic Susceptibility to Hypertension is Associated with. Worse Cognitive Performance in Middle-Aged Persons without Dementia. Cyprien Rivier MD MSc*1 ...

Polygenic Susceptibility to Hypertension is Associated with Worse ...

Background and Objectives Mounting evidence indicates that hypertension leads to a higher risk of dementia. Hypertension is a highly heritable ...

High Genetic Risk for Hypertension Is Associated With Lower...

The study found that, compared to people with low polygenic susceptibility to high systolic blood pressure, those with intermediate risk scored ...

no significant association of polygenic risk scores with ... - Nature

Polygenic risk scores (PRSs) for essential hypertension, calculated from > 900 genomic loci, were recently found to explain a significant ...

Polygenic Interactions With Environmental Exposures in Blood ...

Additionally, polygenic risk scores for BP traits are associated with clinically significant phenotypic variation. However, interactions between ...

Polygenic susceptibility to hypertension is associated with worse ...

Polygenic susceptibility to hypertension is associated with worse cognitive function (2267) ... To read the full-text of this research, you can request a copy ...

A multi-ethnic polygenic risk score is associated with hypertension ...

The HTN-PRS is associated with both prevalent and incident hypertension at 4-6 years of follow up. This association is further confirmed in age-stratified ...

Life-Course Associations between Blood Pressure-Related ... - MDPI

The multi-ancestry genome-wide polygenic risk scores (PRSs) for systolic BP (SBP), diastolic BP (DBP), and hypertension were tested for an association with ...

Polygenic Susceptibility to Hypertension and Cognitive Performance ...

We tested the hypothesis that a higher PSH leads to worse cognitive performance in middle-aged persons without dementia. Confirming this ...

Are polygenic risk scores for systolic blood pressure and LDL ...

PRSSBP was associated with uncontrolled hypertension (odds ratio 1.70; 95% confidence interval: 1.60–1.80) top vs. bottom quintile, equivalent ...

Full article: Genetics of hypertension-related sex differences and ...

The majority of known genetic variation in hypertension and HDP is polygenic. Polygenic risk scores for BP display stronger associations with hypertension risk ...

Study uncovers the role of polygenic risk scores in hypertension ...

Hypertension remains a leading cause of cardiovascular disease. Genetic predispositions account for a significant portion of blood pressure ...

A multi-ethnic polygenic risk score is associated with hypertension ...

A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. ... worse BP category in the follow-up exam ...

Better cardiovascular health in early pregnancy may offset high ...

A validated risk model called a polygenic risk score can be used to predict an individual's chance of developing these conditions based on their ...

Genetic Variants Associated with Hypertension Risk: Progress and ...

The largest GWAS of blood pressure traits to date involved over one million people and identified 901 associated genetic loci [10]. Typically, ...

Polygenic Risk for Type 2 Diabetes in African Americans

... polygenic modeling methods to derive a novel T2D PRS (PRSAA) (11–13). We optimized the score in the Genetics of Hypertension Associated ...