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Posttranslational modification of heme in peroxidases – Impact on ...


Posttranslational modification of heme in peroxidases - PubMed

Four heme peroxidase superfamilies arose independently in evolution. Only in the peroxidase-cyclooxygenase superfamily the prosthetic group is ...

Posttranslational modification of heme in peroxidases – Impact on ...

We demonstrate the autocatalytic posttranslational maturation process and the impact of the covalent links on spectral and redox properties as well as on ...

Posttranslational modification of heme in peroxidases - Impact on ...

Posttranslational modification of heme in peroxidases - Impact on structure and catalysis. · Nicolussi A · Auer M · Sevcnikar B · Paumann-Page M · Pfanzagl V ...

Posttranslational Modification of Heme b in a Bacterial Peroxidase

These autocatalytic posttranslational modifications (PTMs) were shown to strongly influence the biophysical and biochemical properties of these ...

Posttranslational Modification of Heme in Peroxidases - BOKU

Posttranslational Modification of Heme in Peroxidases – Impact on Structure and Catalysis · BOKU Autors · BOKU Organisations ...

Posttranslational modification and heme cavity architecture of ...

Research Article. Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and ...

Posttranslational modification of heme in peroxidases – Impact on ...

Four heme peroxidase superfamilies arose independently in evolution. Only in the peroxidase-cyclooxygenase superfamily the prosthetic group is ...

Posttranslational Modification of Heme b in a Bacterial Peroxidase

These autocatalytic posttranslational modifications (PTMs) were shown to strongly influence the biophysical and biochemical properties of these oxidoreductases.

Common Reactivity and Properties of Heme Peroxidases: A DFT ...

Heme b or post-translationally modified heme present in heme peroxidases serve to catalyse the hydrogen peroxide-mediated one- or two-electron oxidation of ...

Posttranslational modification of heme in peroxidases – Impact on ...

Posttranslational modification of heme in peroxidases – Impact on structure and catalysis · Andrea Nicolussi · Markus Auer · Benjamin Sevcnikar · Martina Paumann- ...

The Relationship of NADPH Oxidases and Heme Peroxidases

The unique feature of the peroxidase-cyclooxygenase superfamily is the presence of a post-translationally modified heme group which is ...

Heme to Protein Linkages in Mammalian Peroxidases - ResearchGate

The impact of heme distortion and asymmetry on the spectral and enzymatic properties is discussed as is the role of the MPO-typical electron withdrawing ...

Posttranslational modification and heme cavity architecture of ...

Semantic Scholar extracted view of "Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal ...

Halogenation Activity of Mammalian Heme Peroxidases - MDPI

In mammals, the phylogenetic peroxidase-cyclooxygenase superfamily of heme peroxidases currently comprises six members: myeloperoxidase (MPO), eosinophil ...

Redox properties of heme peroxidases. - Semantic Scholar

Posttranslational modification of heme in peroxidases - Impact on structure and catalysis. · Biology, Chemistry. Archives of biochemistry and biophysics · 2018.

Post-translational modification as a response to cellular stress ...

Intracellular oxidative stress and oxidative modification of sickle hemoglobin (HbS) play a role in sickle cell disease (SCD) pathogenesis.

Secreted heme peroxidase from Dictyostelium discoideum

The first crystal structure (2.5 Å resolution) of a mycetozoan peroxidase of this superfamily shows the presence of a post-translationally-modified heme with ...

Post‐translational modification and extended glycosylation pattern ...

The refined structure includes 306 amino acid residues, a heme and two calcium ions. The protein belongs to class III peroxidases and is the ...

Posttranslational modification and heme cavity architecture ... - OUCI

Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical ...

(PDF) Posttranslational Modification of Heme b in a Bacterial ...

The existence of covalent heme to protein bonds is the most striking structural feature of mammalian peroxidases, including myeloperoxidase and ...