ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

These disruptive findings provide new insights into the mechanisms underlying brain metastasis with proNGF as a driver of brain metastasis ...

We show that proNGF promotes brain metastasis of breast cancer cells through the formation of the TrkA/EphA2 complex.

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Julien Cicero (1) , Sarah ...

(PDF) ProNGF promotes brain metastasis through TrkA/EphA2 ...

ArticlePDF Available. ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells.

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

The development of brain metastases is particularly harmful in triple-negative breast cancer (TNBC). To date, the mechanisms that induce brain metastasis in ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells ... More importantly, our results showed that ...

Additional file 1 of ProNGF promotes brain metastasis through TrkA ...

Additional file 1 of ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells.

ProNGF increases breast tumor aggressiveness through functional ...

Combinatorial targeting of TrkA and EphA2 dramatically reduced colony formation in vitro, primary tumor growth and metastatic dissemination ...

ProNGF promotes brain metastasis through TrkA/EphA2 ... - Matilda

Matilda - ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells.

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Cicero, Julien; Trouvilliez, Sarah; ...

ProNGF increases breast tumor aggressiveness through functional ...

• EphA2 is a key element of proNGF signaling in breast cancer cells. 44. • ProNGF-induced Src activation through EphA2 is independent of TrkA. 45.

Systems immunology insights into brain metastasis - Cell Press

60. Cicero, J. ... ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Exp ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Auteur(s) : Cicero, Julien [Auteur] Cancer ...

ProNGF increases breast tumor aggressiveness through functional ...

EphA2 is a key element of proNGF signaling in breast cancer cells. •. ProNGF-induced Src activation through EphA2 is independent of TrkA ...

Fig. 3 proNGF enhances trans-BBB migration through Src activation...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Article. Full-text available. Dec 2023.

EphA2: A promising therapeutic target in breast cancer.

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells · Medicine, Biology. Experimental Hematology & ...

BIOMIMESYS® 3D cell culture scaffold as powerful tool to study ...

study, titled “ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells” by Cicero ...

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto ...

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells. Julien Cicero; Sarah ...

TrkA Co-Receptors: The Janus Face of TrkA? - MDPI

... by which EphA2 promotes metastasis via ProNGF. Indeed, in breast cancer, ProNGF stimulation leads to the formation of the TrkA/EphA2/Sortilin complex, which ...

ProNGF increases breast tumor aggressiveness through ... - HAL

Combinatorial targeting of TrkA and EphA2 dramatically reduced colony formation in vitro, primary tumor growth and metastatic dissemination towards the brain in ...