- Protein translocation channel of mitochondrial inner membrane and ...🔍
- Central role of Tim17 in mitochondrial presequence protein ...🔍
- Protein insertion into the inner membrane of mitochondria🔍
- Protein Translocation into the Intermembrane Space and Matrix of ...🔍
- Mechanisms of protein translocation into mitochondria🔍
- Protein Translocation Channels in Mitochondria🔍
- Understanding the molecular mechanism of protein translocation ...🔍
- protein translocation across mitochondrial and plastid outer ...🔍
Protein translocation channel of mitochondrial inner membrane and ...
Protein translocation channel of mitochondrial inner membrane and ...
Two domains of the peripheral membrane protein Tim44 interact with two different sectors of a translocase to coordinate the translocation of ...
Protein translocation channel of mitochondrial inner membrane and ...
The majority of mitochondrial proteins are targeted to mitochondria by N-terminal presequences and use the TIM23 complex for their ...
Protein translocation channel of mitochondrial inner membrane and ...
Our data suggest that the translocation channel and the import motor of the TIM23 complex communicate through rearrangements of the two domains of Tim44.
Central role of Tim17 in mitochondrial presequence protein ... - Nature
The presequence translocase of the mitochondrial inner membrane (TIM23) represents the major route for the import of nuclear-encoded ...
Protein insertion into the inner membrane of mitochondria: routes ...
These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or ...
Protein Translocation into the Intermembrane Space and Matrix of ...
The import motor employs matrix Hsp70 molecules and ATP hydrolysis to ratchet proteins into the mitochondrial matrix. Most IMS proteins lack presequences and ...
Mechanisms of protein translocation into mitochondria - ScienceDirect
The precursors of integral inner membrane proteins of the metabolite carrier family interact with newly identified import components of the intermembrane space ...
Protein Translocation Channels in Mitochondria - SpringerLink
Protein translocation across membranes is a fundamental cellular process that is especially vital for mitochondrial biogenesis.
Understanding the molecular mechanism of protein translocation ...
Using the energy of the membrane potential across the mitochondrial inner membrane and ATP in the matrix, the TIM23 complex mediates translocation of proteins ...
protein translocation across mitochondrial and plastid outer ...
3b provides a satisfying explanation to this problem, because the inner membrane precursors pass through the Tom40 channel and would have no way to access the ...
The dimensions of the protein import channels in the outer and inner ...
The effects of these modifications on translocation across the outer and inner mitochondrial membranes were then determined. Our results show that the internal ...
Targeting and Insertion of Membrane Proteins in Mitochondria
Mitochondrial membrane proteins play an essential role in all major mitochondrial functions. The respiratory complexes of the inner membrane are key for the ...
Protein Transport into the Inner Mitochondrial Membrane - JoVE
Nuclear encoded mitochondrial precursors are imported to the inner membrane in a multistep process involving two separate translocons, TIM22 and TIM23.
Two distinct membrane potential–dependent steps drive ...
Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is ...
The non-canonical mitochondrial inner membrane presequence ...
Tim22, a member of the Tim17/22/23 protein family, forms the translocation channel of this complex. Furthermore, four accessory components, ...
Protein Translocation Across the Outer Membrane of Mitochondria
Transport of nuclear encoded proteins into mitochondria is mediated by distinct translocation machinery in the outer and inner mitochondrial membranes.
The Preprotein Translocation Channel of the Outer Membrane of ...
The preprotein translocase of the outer membrane of mitochondria (TOM complex) facilitates the recognition, insertion, and translocation of nuclear-encoded ...
Mitochondrial membrane transport protein - Wikipedia
Mitochondrial membrane transport proteins, also known as mitochondrial carrier proteins, are proteins which exist in the membranes of mitochondria.
Translocation of mitochondrial inner-membrane proteins
... There is compelling evidence that mitochondrial carrier proteins traverse the Tom40 channel in a loop structure [41, 59, 60]. Hence, two polypeptide ...
The Diversity of the Mitochondrial Outer Membrane Protein Import ...
When compared to the mitochondrial inner membrane, the presented channels are mostly constitutively open and consequently may participate in transport of ...