- Protein unfolding accounts for the unusual mechanical behavior of ...🔍
- Mechanical Unfolding of Proteins—A Comparative Nonequilibrium ...🔍
- Protein Folding Under Mechanical Forces🔍
- What the mechanical forces behind protein folding can tell us about ...🔍
- Anisotropy in mechanical unfolding of protein upon partner|assisted ...🔍
- Direct observation of a force|induced switch in the anisotropic ...🔍
- Mechanically Unfolding the Small🔍
- Mechanical and chemical unfolding of a single protein🔍
Protein unfolding accounts for the unusual mechanical behavior of ...
Protein unfolding accounts for the unusual mechanical behavior of ...
Fibrin seems to behave like an ultra-compressible material due to protein unfolding. The inset shows the Cauchy stress (force per unit current ...
Protein unfolding accounts for the unusual mechanical behavior of ...
We describe the mechanical behavior of isotropic fibrin networks at the macroscopic scale in terms of the nanoscale force response of fibrin molecules that ...
Protein unfolding accounts for the unusual mechanical behavior of ...
Blood clots are built of porous networks of branching fibrin fibers made from the large precursor protein fibrinogen. In vivo, the mechanical properties of ...
Protein unfolding accounts for the unusual mechanical behavior of ...
Request PDF | Protein unfolding accounts for the unusual mechanical behavior of fibrin networks | We describe the mechanical behavior of isotropic fibrin ...
Protein unfolding accounts for the unusual mechanical behavior of ...
Protein unfolding accounts for the unusual mechanical behavior of fibrin networks ... Brown, Multiscale mechanics of fibrin polymer. Gel stretching with protein ...
Mechanical Unfolding of Proteins—A Comparative Nonequilibrium ...
Talin is a focal adhesion protein that is known to extend under mechanical load, and it has been shown to unfold via intermediate states. Here, ...
Protein Folding Under Mechanical Forces: A Physiological View
Mechanical forces regulate the function of numerous proteins relevant to physiology. The functions and folding of proteins have been under scrutiny for ...
What the mechanical forces behind protein folding can tell us about ...
A team of researchers from UWM is using a unique tool view the interaction between proteins to figure out why sometimes cancerous tumors are ...
Anisotropy in mechanical unfolding of protein upon partner-assisted ...
Biomacromolecules, especially proteins with unique viscoelastic properties, primarily serve as force-sensors or conveyors and orchestrate such ...
Direct observation of a force-induced switch in the anisotropic ...
... mechanical unfolding pathway of a protein. Latest updated: February ... behavior of proteins under force and the mechanism of protein folding in ...
Mechanically Unfolding the Small, Topologically Simple Protein L
... unusually well defined pathway in a two-state transition. Finally, by comparing the mechanical unfolding properties of protein L and ubiquitin, which have ...
Mechanical and chemical unfolding of a single protein: A comparison
Single-molecule AFM recordings have the added advantage that they define the reaction coordinate and expose rare unfolding events that cannot be observed in the ...
History, rare, and multiple events of mechanical unfolding of repeat ...
Force spectroscopy experiments using atomic force microscopy on proteins presenting multiple domains have revealed that unfolding forces depend ...
Forced protein unfolding leads to highly elastic and tough ... - Nature
... unfold FL, making FL an ideal candidate for engineering protein hydrogels with unusual mechanical properties. Figure 1: Optical trapping ...
History, rare, and multiple events of mechanical unfolding of repeat ...
Create Free Account. DOI:10.1063/1.5013259; Corpus ID: 4563616. History, rare, and multiple events of mechanical unfolding of repeat proteins. @article ...
Mechanical Unfolding Response of Proteins | Request PDF
amino acid residues) through which tension is applied. This concept, known as mechanical anisotropy, has been demonstrated on folded protein domains ...
History, rare, and multiple events of mechanical unfolding of repeat ...
Mechanical unfolding of proteins consisting of repeat domains is an excellent tool to obtain large statistics. Force spectroscopy experiments using atomic ...
Direct observation of a force-induced switch in the anisotropic ...
Thus, even this simple two-state protein demonstrates a complex mechanical unfolding trajectory, accessing multiple unfolding pathways under ...
Does quantum mechanics play a role in protein folding?
The first figure shows Arrhenius plots for protein folding (notice their unusual ... protein-folding must account for quantum mechanical effects ...
Does protein unfolding play a functional role in vivo? - FEBS Press
This process represents a gain-of-function, as it allows unique responses that integrate mechanical signals with chemical interactions. Finally, ...