Pulmonary toxicity of immune checkpoint immunotherapy

Pulmonary toxicity of immune checkpoint immunotherapy - PMC

Although generally well tolerated, the administration of ICIs can result in unique side effects known as immune-related adverse events (irAEs).

Pulmonary toxicity of immune checkpoint immunotherapy - JCI

Although generally well tolerated, the administration of ICIs can result in unique side effects known as immune-related adverse events (irAEs).

Pulmonary toxicity of immune checkpoint immunotherapy - PubMed

Cancer remains a leading cause of mortality on a global scale. Lung cancer, specifically non-small cell lung cancer (NSCLC), is a prominent ...

Pulmonary Toxicities Associated With the Use of Immune ... - Frontiers

Although the incidence of immune checkpoint inhibitor pneumonitis (ICI-Pneumonitis) is relatively low, this complication is likely to cause the delay or ...

Management of pulmonary toxicity associated with immune ...

Anti-tumour immunotherapy and especially immune-checkpoint inhibitors (ICIs) now take part in the therapeutic strategy of nonsmall cell lung cancer (NSCLC) ...

In NSCLC patients, the tumor has destroyed the lung function, resulting in the patients receiving ICI with a higher risk of CIP. The incidence of CIP in NSCLC ...

Pulmonary adverse events following immune checkpoint inhibitors

Lung toxicity is an uncommon but potentially severe and even fatal complication of ICIs. Timely recognition is critically important but challenging.

Immune-Checkpoint-Inhibitor-Related Lung Toxicity: A Multicentre ...

Background: Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic horizons of various cancers. However, immune-related ...

The knowns & unknowns of pulmonary toxicity following immune ...

Abstract: Since their discovery immune checkpoint inhibitors (ICI) have dramatically changed the treatment landscape for many cancers. In addition to their ...

Diagnosis and management of pulmonary toxicity associated with ...

Although often referred to as pneumonitis, pulmonary toxicity associated with immunotherapy covers a broad and overlapping spectrum of pulmonary manifestations, ...

Severe pulmonary toxicity from immune checkpoint inhibitor treated ...

Here we describe the case of a patient receiving pembrolizumab for non-small cell lung cancer who developed severe checkpoint inhibitor pneumonitis. After ...

Immune checkpoint inhibitor pneumonitis - UpToDate

However, ICIs may also cause immune-related adverse events (irAEs; ie, immune-related toxicities) of varying severity that can affect virtually ...

Pulmonary toxicity of immune checkpoint immunotherapy

Although generally well tolerated, the administration of ICIs can result in unique side effects known as immune-related adverse events (irAEs).

CASE SERIES: SERIOUS PULMONARY TOXICITY SECONDARY ...

INTRODUCTION: Immune checkpoint inhibitors (ICIs) which target the programmed cell death 1 (PD-1) / programmed cell death ligand 1 (PDL-1) pathway [1,2,3] ...

Pulmonary toxicity in patients treated with immune checkpoint ...

Immune checkpoint inhibitors (ICIs) have transformed the oncology treatment landscape. Although immune-related adverse events (irAEs) are ...

Immunotherapy and pulmonary toxicities: can concomitant immune ...

Delaunay et al. [1] presented the results of a retrospective study of 1826 cancer patients treated with immune-checkpoint inhibitors (ICIs). 3.5% of the ...

Immunotherapy Associated Pulmonary Toxicity: Biology Behind ...

The aim of this work is to summarize the biological bases, clinical and radiological findings of lung toxicity under immune checkpoint blockade.

Immune Checkpoint Immunotherapy for Non-Small Cell Lung Cancer

Immune checkpoint inhibitors (ICIs) are newer, immunotherapy-based drugs that have been shown to improve survival in advanced non-small cell lung cancer (NSCLC ...

Pulmonary Toxicity Associated with Immune Checkpoint Inhibitors ...

Immune checkpoint inhibitors (ICIs) have shown efficacy in tumor therapy. However, the risk of pulmonary toxicity from ICI-based treatment ...

Citations to Pulmonary toxicity of immune checkpoint immunotherapy

Pulmonary toxicity of immune checkpoint immunotherapy ... Citation Information: J Clin Invest. 2024;134(2):e170503. https://doi.org/10.1172/ ...