Quantification of Intracellular DNA–Protein Cross|Links with N7 ...

Quantification of Intracellular DNA–Protein Cross-Links with N7 ...

Our DNA-based tandem mass spectrometry analysis reveals that DNA–protein cross-links (DPCMdG) derived from the major product of DNA-methylating ...

Quantification of Intracellular DNA-Protein Cross-Links with N7 ...

The major product of DNA-methylating agents, N7-methyl-2'-deoxyguanosine (MdG), is a persistent lesion in vivo, but it is not believed to ...

Quantification of Intracellular DNA–Protein Cross-Links with N7 ...

Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity.

Quantification of Intracellular DNA-Protein Cross-Links with N7 ...

A tandem mass spectrometry method is developed for quantifying the amounts of MdG and DPCMdG in nuclear DNA by taking advantage of their chemical lability ...

Quantification of Intracellular DNA–Protein Cross-Links with N7 ...

Quantification of Intracellular DNA–Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity. Tingyu Wen 1. ,. Shubo Zhao 2.

Supporting Information: Quantification Of Intracellular DNA-Protein ...

Supporting Information: Quantification Of Intracellular DNA-Protein Cross-Links With N7-. Methyl-2'-deoxyguanosine And Their Contribution To Cytotoxicity.

Quantification of Intracellular DNA-Protein Cross-Links with N7 ...

Quantification of Intracellular DNA-Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity. Tingyu Wen, Shubo Zhao ...

Quantification of Intracellular DNA-Protein Cross-Links with N7 ...

Request PDF | On Apr 23, 2024, Tingyu Wen and others published Quantification of Intracellular DNA-Protein Cross-Links with N7-Methyl-2'-Deoxyguanosine and ...

Quantification of Intracellular DNA-Protein Cross-Links with N7 ...

Quantification of Intracellular DNA-Protein Cross-Links with N7-Methyl-2′-Deoxyguanosine and Their Contribution to Cytotoxicity. CHEMICAL RESEARCH IN ...

DNA-Protein Crosslinks from Environmental Exposure: Mechanisms ...

Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite. Environ Health Perspect 110 Suppl 5:753–756. [DOI] [PMC ...

Cross-linking of the DNA repair protein O 6 - ScienceDirect.com

Cisplatin-induced Lys-Gua cross-links (1,1-cis-diammine-2-(5-amino-5-carboxypentyl)amino-2-(2'-deoxyguanosine-7-yl)-platinum(II) (dG-Pt-Lys) were detected by ...

Histone tails decrease N7-methyl-2′-deoxyguanosine depurination ...

Abasic site formation from MdG is suppressed in NCPs. Furthermore, MdG and histone proteins form cross-links [DNA–protein cross-links (DPCs)], a ...

DNA–protein crosslink proteases in genome stability - Nature

Translocation and stability of replicative DNA helicases upon encountering DNA-protein cross-links. ... dna topoisomerase i as an intracellular ...

The ARK Assay Is a Sensitive and Versatile Method for the Global ...

... quantification of DNA-protein adducts by ELISA-based RADAR assay ... Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA ...

Intracellular Protein Crosslinking Detection Methods

What is intracellular protein crosslinking? A mass spectrometry-based method for protein cross-linking analysis, including sample pretreatment, ...

An Extraction-Free Method by Which a Single Slot Blot can be Used ...

An Extraction-Free Method by Which a Single Slot Blot can be Used to Quantify Intracellular DNA Damage (Crosslinks or Strand Breaks) and Changes in DNA Damage ...

Protein cross-linking by chlorinated polyamines and ... - Nature

Neutrophil extracellular trap (NET) ejected from activated dying neutrophils is a highly ordered structure of DNA and selected proteins ...

Formaldehyde Crosslinking: A Tool for the Study of Chromatin ...

Formaldehyde crosslinking is rou- tinely employed for detection and quantification of protein-. DNA interactions, interactions between chromatin ...

Oxidative Crosslinking of Peptides and Proteins - MDPI

... protein cross-links by singlet oxygen-mediated disulfide oxidation. Redox ... quantification of protein oxidative modifications and amino acid ...

DNA-protein and RNA-protein cross-links in human cells a Cross ...

Epigenetics, the inheritance of genomic information independent of DNA sequence, controls the interpretation of extracellular and intracellular signals in cell ...