RNA and Immunity

RNA Recognition and Immunity—Innate Immune Sensing and Its ...

RNA acts as an immunostimulatory molecule in the innate immune system to activate nucleic acid sensors. It functions as an intermediate, conveying genetic ...

RNA modifications: importance in immune cell biology and related ...

RNA modifications participate in the multiple biological processes of immune cells, including development, differentiation, activation, migration, and ...

Innate immune responses to RNA: sensing and signaling - Frontiers

Innate immune responses to RNA are based on various RNA sensors, including RIG-I, MDA5, ADAR1, TLR3/7/8, OAS1, PKR, NLRP1/6, and ZBP1, via a

RNA Recognition and Immunity-Innate Immune Sensing ... - PubMed

RNA acts as an immunostimulatory molecule in the innate immune system to activate nucleic acid sensors. It functions as an intermediate, ...

Our own RNA triggers an immune response to viral infections

An immune receptor normally known for identifying viral RNA is also capable of binding to cellular RNA to induce immune defenses.

Immune RNA - an overview | ScienceDirect Topics

The self-delivering RNA (sd-rxRNA) interference technology is used to down-regulate immune checkpoints via destroying specific RNAs before they are translated ...

RNA Modification in the Immune System - Annual Reviews

Characterization of RNA modifications has identified their distribution features and molecular functions. Dynamic changes in RNA ...

RNA-based antiviral immunity | Nature Reviews Immunology

In eukaryotic RNA-based antiviral immunity, viral double-stranded RNA is recognized as a pathogen-associated molecular pattern and processed into small ...

The regulation of antiviral innate immunity through non-m6A RNA ...

We provide a systematic introduction to the biogenesis and functions of these non-m 6 A RNA modifications in viral RNA, host RNA, and during virus-host ...

RNA Modification in the Immune System - Annual Reviews

Finally, we emphasize the roles of dysregulated RNA modification during antiviral and antitumor immune responses. 2. THE ROLE OF RNA MODIFICATIONS IN GENE.

Immune RNA - an overview | ScienceDirect Topics

Although both carriers seem to transfer cell mediated immunity, it is accepted that only I-RNA is capable of transferring humoral immunity. What is extremely ...

Innate Immune Evasion by Human Respiratory RNA Viruses

This review attempts to provide a comparative overview of the knowledge about an important part of the interaction between respiratory viruses and their host.

LNCing RNA to immunity: Trends in Immunology - Cell Press

Long noncoding RNAs (lncRNAs) are versatile cell- and context-specific regulators of gene expression and cellular function.

RNA regulatory mechanisms that control antiviral innate immunity

We explore the diverse RNA regulatory mechanisms that modulate the innate antiviral immune response, with a focus on RNA sensing by RIG-I-like receptors (RLR).

5 Questions with an Expert in RNA's Role in Immunity

Sun Hur, HMS associate professor, Department of Biological Chemistry and Molecular Pharmacology ... You research the mysteries of immunity—how the body recognizes ...

RNA Mediated Regulation of Immunity: Mechanism, Disease and ...

Scientific Organizers: Uttiya Basu, Sun Hur and Noam Stern-Ginossar. Date & Location: January 27-30, 2025 | Keystone Resort, Keystone, CO, United States.

Reducing cell intrinsic immunity to mRNA vaccine alters adaptive ...

The incorporation of m1Ψ and cap1 alters protective immunity from mRNA vaccines by altering the innate immune response to the vaccine material.

RNA Mediated Regulation of Immunity: Mechanism, Disease and ...

Joint with: Non-Coding RNA Biology: New Roles and Diversity. RNA Mediated Regulation of Immunity: Mechanism, Disease and Therapeutics. January 27-30, 2025 ...

Searching for clues to how RNA triggers the immune system

mRNA is short for messenger RNA. It is one of several different types of RNA and its role is to deliver the recipe for making proteins to the ...

Snapshot: RNA regulation in immunity - University of York

RNA regulation in immunity ... In the Lagos group, we aim to translate exciting discoveries in RNA Biology to patient benefit through RNA Medicine. Our work ...