Radiobiological Models

The evolution of practical radiobiological modelling - PMC

The linear quadratic (LQ) model is presently the standard method for modelling the influence of radiation dose on cell survival and tissue responses: its ...

The progress of radiobiological models in modern radiotherapy with ...

Radiobiological models are used in modern radiotherapy to evaluate the biological effects of different treatment plans or modalities.

Modelling radiobiology - IOPscience - Institute of Physics

Modelling radiobiology · 1. Introduction · 2. Radiation-induced damage · 3. Responses to damage · 4. Predicting cell survival · 5. Individual ...

Radiobiological modeling and clinical trials

Radiobiological modeling, coupled with reliable predictive assays, can be used to rationalize the selection of patients for particular schedules in trials.

Advances in Radiobiological Modeling in Radiotherapy - Frontiers

Radiotherapy (RT) now represents one of the pillars of cancer treatment and is part of the therapeutic path for a large fraction of cancer patients.

A Mathematical Radiobiological Model (MRM) to Predict Complex ...

A mathematical radiobiological model (MRM) to predict complex DNA damage and cell survival for ionizing particle radiations of varying quality.

Comparison of Three Radiobiological Models in Stereotactic Body ...

This study aims to compare the outcomes predicted by the LQ model with those predicted by two other radiobiological models in stereotactic body radiotherapy ( ...

The sensitivity of radiobiological models in carbon ion radiotherapy ...

Carbon ion radiotherapy (CIRT) relies on relative biological effectiveness (RBE)-weighted dose calculations. Japanese clinics predominantly use ...

Mechanistic, Modeling, and Dosimetric Radiation Biology

A rigorous standardized methodology has been established to assess and quantify the radiation dose absorbed by biological samples.

Radiobiological Models of Tissue Response to Radiation in ...

Biological models of tissue response to radiation, when used wisely, have a potential to be useful in radiation therapy treatment planning. The models can ...

Radiobiological modeling analysis of the optimal fraction scheme in ...

Although SBRT has been widely used for the treatment of early-stage NSCLC, the optimal fraction scheme (FS) has remained unclear. The FS in the ...

The Linear-Quadratic Model and Most Other Common ... - jstor

models in terms of their predicted time-dose relationships. We show that a broad range of radiobiological models are described.

Research in PreClinical Radiation Technology and Radiobiological ...

Radiation Response Modeling. We employ high-performance computing to model radiation transport, interactions with biological systems, and productions of ...

Radiobiological Models: Conventional and Ultra Hypofraction ...

In this study, different fraction sizes in prostate cancer will be examined using a radiobiological model. METHODS. Fifty patients diagnosed ...

Dosimetric validation of two different radiobiological models for ...

The aim of this study was to investigate the normal tissue complication probability (NTCP) for parotid gland of ca tongue patients from two different ...

An overview on the clinical application of radiobiological modeling ...

The results indicate that brachytherapy planning by using CT images causes cold-spots that would influence the resultant TCP. On the other hand, ...

Comparison of Radiobiological Models for Radiation Therapy Plans ...

Purpose: In the current study, using different radiobiological models, tumor control probability (TCP) and normal tissue complication probability (NTCP) of ...

A Comparative Analysis of Radiobiological Models for Cell Surviving ...

Their asymptotes for the cell surviving fractions are exponentials at low as well as high doses, and this is in agreement with the behaviour of the ...

Influence of physical and radiobiological models on evaluation of ...

This study aims to evaluate the radiotherapy planning performance considering the clinical results of glioblastoma multiforme (GBM)-treated patients

Application of Multiple Radiobiological Models in Predicting TCP

Is common to calculate generalized equivalent uniform dose (gEUD) for the target volume and then use the Poisson model to predict tumor control probability ...