Rafts and synapses in the spatial organization of immune cell ...

The multichain immune recognition receptors (MIRRs), including the T cell and B cell antigen receptors and the high affinity receptor for IgE, ...

Abstract. The multichain immune recognition receptors (MIRRs), including the T cell and B cell antigen receptors and the high affinity receptor for IgE, pl.

(PDF) Rafts and synapses in the spatial organization of immune cell ...

PDF | The multichain immune recognition receptors (MIRRs), including the T cell and B cell antigen receptors and the high affinity receptor for IgE,.

Rafts and synapses in the spatial organization of immune cell ...

The evidence now indicates that the Src‐family kinases are concentrated in cholesterol‐ and sphingolipid‐rich membrane microdomains, termed lipid rafts, ...

Membrane Rafts in T Cell Activation: A Spotlight on CD28 ...

In T lymphocytes, this is primarily achieved by the allocation of selected proteins into well-organized structures, such as the immunological synapse (IS)— ...

Rafts and synapses in the spatial organization of immune cell ...

Rafts and synapses in the spatial organization of immune cell signaling receptors. scientific article. In more languages. Spanish. No label defined.

The Role of Protein and Lipid Clustering in Lymphocyte Activation

In each type of synapse, on top of these cell-scale organizational layers on the scale of microns, is nanoscale molecular organization—the ...

Lipid rafts, major histocompatibility complex molecules, and immune ...

M. Dykstra et al. Rafts and synapses in the spatial organization of immune cell signaling receptors. J Leukocyte Biol.

Signaling at the inhibitory natural killer cell immune synapse ... - PNAS

Lipid rafts have been implicated in the organization of the T cell immunological synapse ( ... spatial organization of these molecules at the NK synapse ...

Spatial Organization of Signal Transduction Molecules in the NK ...

Recently, in Jurkat T cell-APC conjugates, PKC-θ was shown to translocate to the membrane lipid rafts in the immune synapse (39). Furthermore, two recent ...

Mechanisms for Size-Dependent Protein Segregation at Immune ...

... spatial organization and signaling of immune cell receptors (1, 2). Immune synapses are specialized cell-cell contacts involving many immune cell-types ...

Signaling Takes Shape in the Immune System - Cell Press

... system and immune systems on molecular organization of synapses are just beginning. ... T cell costimulation by enhancing the association of TCR with rafts.

Spatial organization of transmembrane receptor signalling

... raft hypothesis: lipid rafts play a role in immune cell activation. ... Groves JT (2006) Spatial mutation of the T cell immunological synapse.

Microenvironment mapping via Dexter energy transfer on immune ...

... synaptic T cell (trans-labeling) (Fig. 4A). As a control ... Cellular-scale proximity labeling for recording cell spatial organization ...

The integration of signaling and the spatial organization of the T cell ...

(2011). The immunological synapse: a cause or consequence of T-cell receptor triggering? Immunology 133, 420–425. Pubmed Abstract | Pubmed Full ...

Arp2/3 complex-driven spatial patterning of the BCR ... - eLife

How the spatial organization of the BCR at the immune synapse impacts BCR signaling and B cell activation is not fully understood. Because ...

Dynamics and spatial organization of Kv1.3 at the immunological ...

3 internalization and release in extracellular vesicles. Significance. During T cell activation through an immunological synapse (IS), potassium ...

Signaling at the inhibitory natural killer cell immune synapse ... - PNAS

Rafts are known to carry many activating signal transduction molecules in other immune cell systems (5, 8, 9); the spatial organization of these.

Impaired TCR signaling through dysfunction of lipid rafts in ...

They have been implicated in the cytoskeletal re-organization that forms platform immunological synapses at the cell membrane, which are ...

The Size of the Synaptic Cleft and Distinct Distributions of ...

Assembly of the immunological synapse for T cells and NK cells. ... Rafts and synapses in the spatial organization of immune cell signaling receptors.