Recent advances and challenges in antibacterial drug development

The analysis covers traditional direct-acting small molecules and nontraditional antibacterial agents in clinical and preclinical development worldwide.

Since the beginning of the century, Big Pharma began exiting antibacterial drug discovery despite a growing clinical need [2]. Apart from financial issues and ...

Recent advances and challenges in antibacterial drug development

Gigante, V., Sati, H., & Beyer, P. (2022). Recent advances and challenges in antibacterial drug development. ADMET and DMPK, 10(2), 147–151.

Recent advances and challenges in antibacterial drug development

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Recent advances and challenges in antibacterial drug development

Recent advances and challenges in antibacterial drug development; The editorial ... The Directory of Open Access Journals. Open Global Trusted. © DOAJ 2024 ...

WHO releases report on state of development of antibacterials

Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for new, ...

Recent advances and challenges in antibacterial drug development

PDF | There is a continuing need for new antibacterial drugs to deal with the burgeoning of bacterial pathogens resistant to the existing ...

An Overview of the Recent Advances in Antimicrobial Resistance

Advancements in novel therapeutics (e.g., alternative antimicrobial agents and vaccines) offer promising avenues in addressing AMR challenges. Policy ...

Recent advances and challenges in antibacterial drug development.

Recent advances and challenges in antibacterial drug development. ... Impact Initiatives and Research Coordination Unit, Global Coordination Department, AMR ...

Current challenges and advancements towards discovery and ...

In this review, the era of antibiotic discovery along with recent advances in discovery/development and manufacturing, mechanism of action, and cellular ...

Polymyxins: recent advances and challenges - Frontiers

Without effective management and scaling up the supply of antibiotics, nearly 10 million people worldwide are expected to die from drug-resistant infections by ...

Antibacterial Drug Development: Challenges, Recent Developments ...

A decline in antibacterial drug development coupled with emerging bacterial resistance has resulted in limited treatment options.

Small-Molecule Antibiotic Drug Development: Need and Challenges

While scientists focused on discovering new medicines may not think of economic incentives as a fundamental problem, perverse incentives in the ...

Antibiotics in the clinical pipeline as of December 2022 - Nature

The need for new antibacterial drugs to treat the increasing global prevalence of drug-resistant bacterial infections has clearly attracted ...

Recent Advances in Pharmaceutical Approaches of Antimicrobial ...

Globally, the increase of pathogenic bacteria with antibiotic-resistant characteristics has become a critical challenge in medical treatment.

Challenges and opportunities for incentivising antibiotic research ...

A review of funding applications for antibiotic drug discovery projects by SMEs and academia identified several scientific and technical ...

Recent advances and challenges in antibacterial drug development

Recent advances and challenges in antibacterial drug development: Editorial. Lynn Silver. LL Silver Consulting, New Jersey, United States;. silverly@comcast ...

Brief Overview of Approaches and Challenges in New Antibiotic ...

The drug discovery landscape was forever changed after the arrival of penicillin. Not only did it save thousands of lives, it also ushered in an era of natural ...

Progress and New Challenges in Combatting the Threat of ...

While antibacterial drug development has improved over the past decade, it is important to recognize that progress has been slow and significant obstacles ...

Challenges and opportunities in the discovery, development, and ...

Antimicrobial resistance is a direct result of antibiotic use. · Indiscriminate and excessive use of broad-spectrum antibiotics exacerbates the problem.