Recent advances in nanoparticulate RNA delivery systems

Recent advances in nanoparticulate RNA delivery systems - PNAS

Here, we discuss the preclinical and clinical advancement of new generations of RNA delivery therapies along multiple axes.

Recent advances in nanoparticulate RNA delivery systems - PubMed

Nanoparticle-based RNA delivery has shown great progress in recent years with the approval of two mRNA vaccines for Severe Acute Respiratory ...

Recent advances in nanoparticulate RNA delivery systems

Recommended publications · Lipid Nanoparticle (LNP) Enables mRNA Delivery for Cancer Therapy · From structural design to delivery: mRNA ...

Drug delivery systems for RNA therapeutics | Nature Reviews Genetics

Many non-viral RNA delivery systems also utilize polymers and polymeric nanoparticles (Fig. 3a). Chemists can vary polymer traits including ...

Recent Advances in Site-Specific Lipid Nanoparticles for mRNA ...

Site-specific lipid nanoparticles (LNP) for mRNA delivery. mRNA-loaded LNP is composed of ionizable lipid, helper lipid, cholesterol, and PEG ...

Recent advances in nanoparticulate RNA delivery systems

Nanoparticle-based RNA delivery has shown great progress in recent years with the approval of two mRNA vaccines for Severe Acute Respiratory Syndrome ...

Advances in the polymeric nanoparticulate delivery systems for RNA ...

RNA therapeutics have emerged as potential treatments for genetic disorders, infectious diseases, and cancer. RNA delivery to target cells for efficient ...

Current landscape of mRNA technologies and delivery systems for ...

This lipid nanoparticle (LNP)-encapsulated small interfering RNA (siRNA) was approved by the United States Food and Drug Administration (FDA) ...

Advances and prospects of RNA delivery nanoplatforms for cancer ...

Nanoplatforms, particularly lipid and polymeric nanoparticles, provide designed means to address the challenges of RNA delivery and cellular ...

RNA delivery systems - PNAS

Two of these vaccines were lipid nanoparticles (LNPs) formulated to carry mRNA. Other LNP-RNA drugs, including those that edit (2) or silence (3 ...

Enhancing RNA-lipid nanoparticle delivery: Organ- and cell ...

Recent advancements in RNA therapeutics highlight the critical need for precision gene delivery systems that target specific organs and cells.

Recent Advances in RNA Therapeutics and RNA Delivery Systems ...

In this manner, nanoparticle-based delivery systems, which would enable not only stable delivery but also a protection of the loaded RNA cargo, ...

Recent Advances in RNA Therapeutics and RNA Delivery Systems ...

6, 7 Currently, there are several mRNA delivery vehicle tools available, including lipid-based nanoparticles and viral vectors. 8,9 Lipid-based nanoparticles ( ...

Advances in the delivery of RNA therapeutics - Genome Medicine

Of the non-viral RNA delivery vehicles, nanoparticles are perhaps the most studied. Nanoparticle encapsulation of RNA physically protects ...

Recent Advances in the Lipid Nanoparticle-Mediated Delivery of ...

Lipid nanoparticles (LNPs) have recently emerged as one of the most advanced technologies for the highly efficient in vivo delivery of exogenous mRNA, ...

Lipid nanoparticles-based RNA therapies for breast cancer treatment

LNPs overcome several limits of conventional delivery systems, such as low delivery efficiency and immune responses triggered by naked nucleic ...

Recent advances in targeted delivery of non-coding RNA-based ...

In this review, we discuss the latest developments in nanoparticles to aid ncRNA-based drug development, particularly miRNA, and we analyze the current ...

Nanoparticle delivery systems for siRNA-based therapeutics

The major challenge in using RNAi for disease therapy is the targeted and effective delivery of siRNA in vivo. The development of nanotechnology with the ...

Lipid nanoparticles for mRNA delivery | Nature Reviews Materials

Progress in mRNA technologies and lipid nanoparticle-based delivery systems has allowed the development of mRNA COVID-19 vaccines at ...

Advances in Nanoparticles for Effective Delivery of RNA Therapeutics

In a recent study, mRNA delivery systems based on CPP PepFect 14 (PF14) nanoparticles and LNPs were compared to measure detectable reporter ...