Regulation of a pentameric ligand|gated ion channel by a ...

Regulation of a pentameric ligand-gated ion channel by a ...

This work details type-specific lipid interactions, which adds to our growing understanding of how lipids modulate pLGICs.

Regulation of a pentameric ligand-gated ion channel by a ... - PubMed

Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from bacteria to humans.

Regulation of pentameric ligand-gated ion channels by ... - Cell Press

Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from ...

Open-channel structure of a pentameric ligand-gated ion ... - Nature

Pentameric ligand-gated ion channels (pLGICs) mediate synaptic transmission and are sensitive to their lipid environment.

Allosteric regulation of pentameric ligand-gated ion channels - HAL

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a ...

Allosteric regulation of pentameric ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a ...

Allosteric regulation of pentameric ligand-gated ion channels - HAL

Pentameric ligand-gated ion channels (pLGICs) play a cen- tral role in intercellular communications in the nervous sys- tem by converting the ...

A gating mechanism of pentameric ligand-gated ion channels - PNAS

Pentameric ligand-gated ion channels (pLGICs) control membrane conductance in living systems from bacteria to humans. ... The latter is initiated by the outward ...

Gating of Pentameric Ligand-Gated Ion Channels: Structural Insights ...

Pentameric ligand-gated ion channels (pLGICs) mediate fast synaptic communication by converting chemical signals into an electrical response.

Insights and Incongruities in Pentameric Ligand-gated Ion Channel ...

The superfamily of pentameric ligand-gated ion channels (pLGICs) comprises key players in electrochemical signal transduction across evolution, ...

Pentameric Ligand-Gated Ion Channels as Pharmacological Targets ...

The ion fluxes through pLGICs generate transient changes in the membrane potential, allowing the dynamic control of the neuronal excitability. Recent ...

Crystal structures of a pentameric ligand-gated ion channel ... - PNAS

Pentameric ligand-gated ion channels (pLGICs) are a superfamily of membrane receptors that mediate fast chemical transmission of nerve signals in the central ...

Regulation of a pentameric ligand-gated ion channel by a semi ...

Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from ...

Regulation of a pentameric ligand-gated ion channel by a ... - OUCI

Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site ... Authors: Akshay Sridhar; Sarah C.R. Lummis; Diletta Pasini ...

Structural basis for the modulation of pentameric ligand-gated ion ...

Pentameric ligand-gated ion channels (pLGICs) play a central role in synaptic communication and are implicated in a plethora of neurological disorders ...

Allosteric regulation of pentameric ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical ...

Allosteric regulation of pentameric ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the ...

Regulation of a pentameric ligand-gated ion channel ... - R Discovery

Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from ...

Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion ...

TRP channels are a superfamily of cation-selective channels that are implicated in many physiologic functions including temperature sensation and regulated by ...

Chasing the open-state structure of pentameric ligand-gated ion ...

In the case of the superfamily of nicotinic-receptor channels (also referred to as pentameric ligand-gated ion channels [pLGICs]), for example, two different ...