Regulation of immune responses by the airway epithelial cell ...

The airway epithelium is an immunologically active barrier surface that senses changes in the airway environment and interacts with resident and recruited ...

Modulation of innate immunity in airway epithelium for host-directed ...

The airway epithelial cells together with stromal cells and tissue-residing immune cells shape immune responses in the local environment. Those ...

Control of local immunity by airway epithelial cells

To avoid chronic inflammation, the pulmonary system has developed specific means to control local immune responses. Even though airway epithelial cells can act ...

Regulation of immune responses by the airway epithelial cell ...

The community of cells lining our airways plays a collaborative role in the preservation of immune homeostasis in the lung and provides protection from the ...

Epithelial Cell Regulation of Immune Responses in the Lung

In this chapter, we will discuss how the airway epithelium induces Th2 responses in the lung and how it can also dampen inflammation in some cases.

Epithelium: At the interface of innate and adaptive immune responses

This review highlights new data suggesting that epithelial cells mediate innate immune responses and regulate adaptive immune responses.

[PDF] Regulation of immune responses by the airway epithelial cell ...

This Review discusses how the view of the airway epithelial landscape has evolved with the advent of transcriptomic approaches to cellular phenotyping, ...

The innate immune function of airway epithelial cells in inflammatory ...

It acts as the first barrier in the defence against a wide range of inhaled challenges, and is critically involved in the regulation of both innate and adaptive ...

Airway Epithelial Innate Immunity - Frontiers

Besides providing an essential protective barrier, airway epithelial cells directly sense pathogens and respond defensively. This is a frontline ...

Control of local immunity by airway epithelial cells - Nature

However, it has become clear that airway epithelial cells have a much more active role in the initiation of immune reactions. Besides the ...

Airway epithelial regulation of pulmonary immune homeostasis and ...

We review the role of the airway epithelium in inflammation and immunity. We focus on epithelial cell immune regulation triggered by environmental signals.

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

Airway epithelial cells regulate both innate and adaptive immunity through production of functional molecules and physical interactions with ...

Regulation of immune responses by the airway epithelial cell ...

The community of cells lining our airways plays a collaborative role in the preservation of immune homeostasis in the lung and provides protection from the ...

Mechanisms of airway epithelial injury and abnormal repair in ...

Apart from its important role as a barrier, the airway epithelium is also involved in the regulation of the innate immune response. Airway epithelial cells ...

Regulation of immune responses by the airway epithelial cell ... - OUCI

Proc. Natl Acad. Sci. USA 107, 3210–3215 (2010). This article shows how chemosensory cells in the airways mediate reflex reactions to irritants, including ...

Regulation of local immunity by airway epithelial cells

Mechanisms by which epithelial cells regulate mucosal immune responses, thus creating an organ-specific microenvironment, including local adaptations in ...

Control of local immunity by airway epithelial cells. - Abstract

To avoid chronic inflammation, the pulmonary system has developed specific means to control local immune responses. Even though airway epithelial cells can act ...

Regulation of Immune Responses by Nonhematopoietic Cells in ...

In addition to their well-established roles in gas exchange and barrier function, lung epithelial cells express an armament of innate sensors ...

Airway epithelial cells modify immune responses by inducing an anti ...

However, expression of negative regulatory PD-L1 (CD274) was increased and dendritic cell induced proliferation of T lymphocytes was diminished.

Control of epithelial immune-response genes and implications for ...

In that context, we have proposed that epithelial cells lining the airway provide critical biochemical signals for immune-cell influx and activation and that ...