Regulation of vascular endothelial growth factor receptor 2 ...

Regulation of vascular endothelial growth factor receptor 2 ... - NCBI

We show that inhibition of syntaxin 6, a Golgi-localized target membrane-soluble N-ethylmaleimide attachment protein receptor (t-SNARE) protein, interferes ...

VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 ...

Vascular endothelial growth factor receptor 2 (VEGFR2) is a primary responder to vascular endothelial growth factor signal, and thereby regulates ...

Regulation of Vascular Endothelial Growth Factor Receptor-2 ...

In spite of these advances, the mechanisms underlying the regulation of VEGFR-2 activity remain poorly understood. The EC response to VEGF is increased by cell ...

Vascular endothelial growth factor receptor 2 - P35968 - UniProt

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular ...

Regulation of Vascular Endothelial Growth Factor Receptor 2 ...

Our findings underscore for the first time the key role played by the VEGFR2-HSP90-RhoA-ROCK-FAK/Tyr 407 pathway in transducing the VEGF signal.

Downregulation of vascular endothelial growth factor receptor-2 ...

We suggest that redundant ROS reduces VEGFR-2 through β-TrCP-mediated VEGFR-2 degradation, which is postulated to be regulated by GSK-3β.

Down-regulation of Vascular Endothelial Growth Factor Receptor 2 ...

VEGF-induced capillary-like structures formed by endothelial cells were coincubated with ALLN, MG132, and lacatcystin and analyzed 12 hours after seeding on ...

Vascular Endothelial Growth Factor Receptor (VEGFR-2)/KDR ...

Early embryogenesis and lymphangiogenesis processes are regulated by VEGF-C/D and their parent receptor VEGFR-3 [18,19]. Amongst three VEGF receptors, VEGFR-2 ...

Purinergic regulation of vascular endothelial growth factor signaling ...

We tested the hypothesis that activated P2Y1 receptors transactivate vascular endothelial growth factor receptor (VEGFR-2) in angiogenic ...

Glycocalyx regulation of vascular endothelial growth factor receptor ...

In the endothelium, VEGF mediates most of its angiogenic effects through VEGF receptor 2 (VEGFR2). To understand the role of EMCN, we examined the effect of ...

Transcriptional regulation of the Vascular Endothelial Growth Factor ...

Forced AP-2 expression decreased the capacity of tumor formation induced by prostatic tumor cells in nude mice, which coincides with a 15-fold reduction in VEGF ...

Interactions of VEGFR-1 and VEGFR-2 in Endothelial Cell Signaling

Vascular endothelial growth factor (VEGF) plays a central role in vascular homeostasis. VEGF receptors (VEGFRs) include several subtypes ...

Vascular Endothelial Growth Factor Receptor-2 Expression Is ...

Vascular endothelial growth factor receptor-2 kinase insert domain receptor (VEGFR2/KDR) is critical for angiogenesis, and VEGFR2 mRNA and protein are ...

Kdr - Vascular endothelial growth factor receptor 2 | UniProtKB

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of ...

Molecular Bases of VEGFR-2-Mediated Physiological Function and ...

The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial roles in vasculogenesis and angiogenesis. Angiogenesis ...

Regulation of vascular endothelial growth factor (VEGF) gene ...

In cells cotransfected with ERα, E2 induced 3.2-fold induction in VEGF-promoter luciferase activity. A 2.3-fold increase was observed in cells cotransfected ...

Vascular Endothelial Growth Factor Receptor-2

Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and ...

Regulation of vascular endothelial growth factor receptor-2 in ...

Vascular endothelial growth factor receptor-2 (VEGFR2) is a key angiogenic factor, and angiogenesis is an important physiological process ...

Vascular endothelial growth factor receptor-2: structure, function ...

Semantic Scholar extracted view of "Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition.

Regulation of Vascular Endothelial Growth Factor Receptor Function ...

Signaling of VEGF-A through its receptor vascular endothelial growth factor receptor 2 (VEGFR2) promotes endothelial cell (EC) proliferation ...