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Rescue of Locomotor Impairment in Dopamine D2 Receptor ...


Rescue of locomotor impairment in dopamine D2 receptor ... - PubMed

In this article, D2R-/- mice were used to explore the possibility that an A2AR antagonist might reestablish their motor impairment.

Rescue of Locomotor Impairment in Dopamine D2 Receptor ... - NCBI

In this article, D2R−/− mice were used to explore the possibility that an A2AR antagonist might reestablish their motor impairment.

Rescue of Locomotor Impairment in Dopamine D2 Receptor

Rescue of Locomotor Impairment in Dopamine D2 Receptor-. Deficient Mice by an Adenosine A2A Receptor Antagonist. Shiro Aoyama,1,2 Hiroshi Kase,2 and Emiliana ...

Rescue of Locomotor Impairment in Dopamine D2 Receptor ...

Rescue of Locomotor Impairment in Dopamine D2 Receptor-Deficient Mice by an Adenosine A2A Receptor Antagonist · Article · Figures & Data · Info & ...

Rescue of locomotor impairment in dopamine D2 receptor-deficient ...

Rescue of locomotor impairment in dopamine D2 receptor-deficient mice by an adenosine A2A receptor antagonist. Aoyama, S; Kase, H; Borrelli, E. Affiliation.

Object recognition impairment and rescue by a dopamine D2 ...

The results indicate that a mild enhancement of dopaminergic levels can be detrimental to object recognition, and that this deficit can be rescued by a low dose ...

Parkinsonian-like locomotor impairment in mice lacking dopamine ...

This study shows that D2 receptors have a key role in the dopaminergic control of nervous function, using homologous recombination to generate ...

Rescue of Locomotor Impairment in Dopamine D2 Receptor ...

Article "Rescue of Locomotor Impairment in Dopamine D2 Receptor-Deficient Mice by an Adenosine A2A Receptor Antagonist." Detailed information of the ...

How do adenosine A2A receptor antagonists impact dopamine D2 ...

... receptor antagonists impact dopamine D2 receptor-deficient mice's locomotor impairment ... receptor antagonists impact dopamine D2 receptor ... Rescue of Locomotor ...

Altered GABAergic neurotransmission in mice lacking dopamine D2 ...

These results suggest that the absence of D2R alters the GABAergic neurotransmission, specifically on GABAA-receptor mediated signaling, and stimulating the ...

Restoration of KCC2 Membrane Localization in Striatal Dopamine ...

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat ...

Dopamine D2 receptor dysfunction is rescued by adenosine A2A ...

Conversely, postsynaptic D2R function in hMT mice was impaired, as suggested by the inability of a D2R agonist to re-establish normal corticostriatal synaptic ...

Dopamine/adenosine interactions related to locomotion and tremor ...

The impairment of locomotion shown by D2 receptor-deficient mice was rescued by the aden- osine A2A antagonist KW-6002 [21]. Systemic injections of the ...

Enhanced GABA Transmission Drives Bradykinesia Following Loss ...

Here we show that selective deletion of DA D2 receptors (D2Rs) from indirect-pathway medium spiny neurons (iMSNs) is sufficient to impair locomotor activity, ...

Restoration of KCC2 Membrane Localization in Striatal Dopamine ...

... Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice ... Dopamine D2 receptor-expressing medium ...

Role of Striatal D1 and Extra-striatal D2 Dopamine Receptors

In fact, dopamine antagonists also impair motor coordination during voluntary wheel running [20, 32, 34, 54]. This suggests a common neural ...

The Human D2 Dopamine Receptor Synergizes with the A2A ...

Rescue of locomotor impairment in dopamine D2 receptor-deficient mice by an adenosine A2A receptor antagonist. J Neurosci 20: 5848–5852 ...

Dopamine Receptors and Parkinson′s Disease - Hisahara - 2011

In contrast to disruption of D1 receptor subfamily, spontaneous PD-like locomotor impairment is found in D2 receptor subfamily knockout mice. D2 receptor- ...

RGS9‐2 rescues dopamine D2 receptor levels and signaling in ...

Dopamine D2 receptor signaling is central for striatal function and movement, while abnormal activity is associated with neurological disorders including ...

The novel adenosine A2A antagonist Lu AA47070 reverses ... - OUCI

Aoyama, Rescue of locomotor impairment in dopamine D2 receptor-deficient mice by an adenosine A2A receptor antagonist, J Neurosci, № 20, с. · Bara-Jimenez, ...