Review Clinical and genetic issues in dilated cardiomyopathy

Clinical and genetic issues in dilated cardiomyopathy: A review for ...

Dilated cardiomyopathy (DCM) has recently emerged as having a genetic basis, much as did hypertrophic cardiomyopathy last decade.

Clinical and genetic issues in dilated cardiomyopathy - PubMed

Dilated cardiomyopathy (DCM), usually diagnosed as idiopathic dilated cardiomyopathy (IDC), has been shown to have a familial basis in 20-35% of cases.

Clinical and genetic issues in familial dilated cardiomyopathy

Dilated cardiomyopathy was discovered in 65 subjects from 48 of the 445 families (10.8%) as determined by full cardiac evaluation or at autopsy. Of the 65 ...

Clinical and Genetic Issues in Familial Dilated Cardiomyopathy

Dilated cardiomyopathy in the era of precision medicine: latest concepts and developments. Heart Failure Reviews, 10.1007/s10741-021-10139-0, 27(4): 1173 ...

Clinical and Genetic Investigations of 109 Index Patients With ...

Background: It was the aim to investigate the frequency and genetic basis of dilated cardiomyopathy (DCM) among relatives of index patients with ...

Clinical and genetic issues in dilated cardiomyopathy: A review for ...

Dilated cardiomyopathy (DCM), usually diagnosed as idiopathic dilated cardiomyopathy (IDC), has been shown to have a familial basis in 20-35% of cases.

Update 2011: Clinical and Genetic Issues in Familial Dilated ...

Now panels of dozens of genes at reduced cost, incorporating many or all reported for any of the genetic cardiomyopathies (DCM, HCM, restrictive cardiomyopathy, ...

Clinical Implication of Genetic Testing in Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is one of the important causes of heart failure (HF). With the rapidly evolving technologies for gene analysis ...

Evidence-Based Assessment of Genes in Dilated Cardiomyopathy

Idiopathic dilated cardiomyopathy (DCM), compared with other genetic cardiomyopathies, demonstrates marked locus heterogeneity, with many genes ...

Dilated cardiomyopathy | Nature Reviews Disease Primers

Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or biventricular dilation and impaired contraction ...

Atlas of the clinical genetics of human dilated cardiomyopathy

Dilated cardiomyopathy (DCM) accounts for 30–40% of all heart failure cases in large clinical trials and is the leading cause of heart transplantation. There is ...

Comprehensive review on gene mutations contributing to dilated ...

DCM is also the most common cause of chronic congestive heart failure and sudden cardiac death in individuals aged 20–60, as well as the leading cause of heart ...

Prevalence of Genetically Associated Dilated Cardiomyopathy

Background: Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation globally. Disease-associated genetic ...

Clinical and genetic issues in familial dilated cardiomyopathy

Clinical Insights in RNA-Binding Protein Motif 20 Cardiomyopathy: A Systematic Review ... Cardiac Troponin I Mutations in Hereditary Cardiomyopathies.

Genetics of Dilated Cardiomyopathy - Annual Reviews

In addition to standard treatment of heart failure and prevention of arrhythmias and sudden cardiac death, patients with genetic cardiomyopathy ...

Dilated cardiomyopathy: from epidemiologic to genetic phenotypes

Dilated cardiomyopathy (DCM) belongs to the primary and mixed cardiomyopathies. Secondary cardiomyopathies affect the heart as part of a ...

Genetics of dilated cardiomyopathy - UpToDate

INTRODUCTION. Dilated cardiomyopathy (DCM) is a common cause of heart failure (HF) and is the most common diagnosis in patients referred for ...

The addition of genetic testing and cardiovascular magnetic ...

Dilated cardiomyopathy (DCM) is a common phenotype manifest in a diverse group of patients due to a combination of genetic and acquired susceptibility.

Clinical and genetic issues in dilated cardiomyopathy - ResearchGate

... Dilated cardiomyopathy (DCM) is defined by reduced systolic cardiac function resulting from enlargement and thinning of the left ventricular ...

Challenges and Applications of Genetic Testing in Dilated ...

Genetic tests for dilated cardiomyopathy (DCM) have a diagnostic yield of up to 40%, but there is significant genetic heterogeneity and other challenges.