Review article CRISPR/Cas9|based application for cancer therapy

Review article CRISPR/Cas9-based application for cancer therapy

The greatest challenge of CRISPR/Cas9 for cancer therapy lies on how to deliver it to the target tumor site safely and effectively.

Application of CRISPR/Cas9 Technology in Cancer Treatment

CRISPR/Cas9 may treat gene-level tumors. CRISPR/Cas9-based personalized and targeted medicines may shape tumor treatment. This review examines ...

Comprehensive review of CRISPR-based gene editing

There are several different CRISPR-based strategies that have been proposed for cancer therapy [4]. One approach is to inactivate genes that ...

Current Status of CRISPR/Cas9 Application in Clinical Cancer ...

Several studies have used the CRISPR-Cas9 technique for editing cancer cell genomic DNA in cells and animal cancer models and have shown therapeutic potential ...

Engineering CRISPR/Cas9 therapeutics for cancer precision medicine

In this review, we showcase studies and preclinical trials that show the utility of CRISPR/Cas9 in disrupting oncogenic targets, modulating ...

CRISPR in cancer biology and therapy | Nature Reviews Cancer

In cancer research, CRISPR and related tools have offered a window into previously intractable problems in our understanding of cancer genetics, ...

Recent advances and applications of CRISPR-Cas9 in cancer ...

Cancer immunotherapy aims to activate the immune system in an inhibitory condition due to the TME, restoring its ability to kill tumor cells [40] ...

CRISPR/Cas9 therapeutics: progress and prospects - Nature

Promising applications for this technology include the treatment of cancers, cardiovascular diseases, sickle cell anemia, and neurodegenerative ...

A Novel Anti-Cancer Therapy: CRISPR/Cas9 Gene Editing - Frontiers

However, the potential off-target effect limits its clinical application, and the effective ethical review is necessary. The article reviews the ...

CRISPR/Cas9-Mediated Genome Editing in Cancer Therapy - MDPI

In cancer research, the intricate genetic mutations in tumors have promoted extensive utilization of the CRISPR/Cas9 system due to its efficient ...

CRISPR/Cas9: Role of genome editing in cancer immunotherapy

Moreover, CRISPR-CAS9 has been employed to engineer the oncolytic virus for cancer therapy. In this review, we discussed the development of the CRISPR/CAS9 ...

Exposing cancer with CRISPR-Cas9: from genetic identification to ...

This review focuses on the application of CRISPR-Cas9 system for cancer research and therapy, including oncogene identification, genetic screen, druggable ...

Review of applications of CRISPR-Cas9 gene-editing technology in ...

Application of CRISPR-Cas9 gene-editing technology in cancer research has aroused great interest, promoting the exploration of the molecular ...

Targeting Cancer with CRISPR/Cas9-Based Therapy - MDPI

Gene editing with CRISPR/Cas9-based tools now enables the precise and permanent targeting of mutations and offers an opportunity to harness this technology to ...

CRISPR/Cas9 for cancer treatment: technology, clinical applications ...

Thus, CRISPR-Cas9 system has been applied in tumor treatment research more and more. In this review, we aim to illustrate CRISPR-Cas ...

Frontiers of CRISPR-Cas9 for Cancer Research and Therapy

This review summarizes some of the recent developments and preclinical applications of CRISPR-Cas9 technology in cancer research and therapy.

Research into overcoming drug resistance in lung cancer treatment ...

While continual enhancements in CRISPR-Cas9 technology are of paramount importance, its application in addressing existing clinical challenges ...

Application of the CRISPR/Cas9 System to Drug Resistance in ...

The CRISPR/Cas9 system is poised to play an important role in preventing drug resistance in breast cancer therapy and will become an essential ...

Crispr-cas9 for the treatment of lung cancer - Dove Medical Press

For example, if the CRISPR-Cas9 system disables the expression of cancer receptors on lymphocytes, it decreases the contact between the tumor ...

How CRISPR Is Changing Cancer Research and Treatment - NCI

CRISPR is a fairly new and highly precise gene editing tool that is changing cancer research and treatment. Researchers are using CRISPR to ...