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Revisiting Epidermal Growth Factor Receptor


Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification ...

We investigated the genomic landscape of EGFR amplification in blood-derived cell-free tumor DNA (cfDNA) across diverse cancers and the role of anti-EGFR ...

Revisiting epidermal growth factor receptor in glioblastoma multiforme

The EGFR negative cases appear to respond better to therapy, however, the difference is not statistically significant (P = 0.298). Further, EGFR protein ...

Revisiting epidermal growth factor receptor in glioblastoma multiforme

Epidermal growth factor receptor (EGFR) has been implicated as the primary contributor to glioblastoma initiation and succession. The present study was designed ...

Revisiting a controversy: The effect of EGF on EGFR dimer stability

Our measurements show that the dissociation constant is decreased ~150 times due to ligand binding, indicative of significant dimer stabilization.

Faculty who have authored ... - Faculty Collaboration Database

Faculty who have authored publication Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free ...

Epidermal growth factor receptor revisited: Prognostic marker or ...

Abstract. Commentary to: EGFR expression variance in paired colorectal cancer primary and metastatic tumors. Nirit Yarom, Celia Marginean, Terence Moyana, ...

[PDF] Revisiting Epidermal Growth Factor Receptor (EGFR ...

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With ...

Analysis of Cell-Free Circulating Tumor DNA in Patients ... - Altmetric

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With ...

Revisiting Epidermal Growth Factor Receptor ( EGFR ) Amplification ...

Nine evaluable patients with EGFR amplification were treated with anti-EGFR-based regimens; five (55.6%) achieved partial responses, including three patients ...

Revisiting Clinical Trials Using EGFR Inhibitor-Based Regimens in ...

Activation of the epidermal growth factor receptor (EGFR) signaling pathway is known to play a significant role in the pathophysiology of non- ...

Time to Revisiting Inhibition of Epidermal Growth Factor Receptor in ...

Giroux et al. [12] reported the case of a man with lung cancer and psoriasis with response of the skin lesions to erlotinib 3 months after the ...

Epidermal Growth Factor Receptor Targeting in Non-Small Cell ...

Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) have changed the paradigm of treatment in non-small cell lung cancer (NSCLC). Th.

Targeting Epidermal Growth Factor Receptor for Cancer Treatment

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, is activated by ligand binding, overexpression, or mutation. It is well ...

Novel anticancer targets: revisiting ERBB2 and discovering ERBB3

The Erbb family consists of four closely related type 1 transmembrane tyrosine kinase receptors: the epidermal growth factor receptor (EGFR; ...

Diabetic Foot Ulcers and Epidermal Growth Factor: Revisiting the ...

Historical studies implicate an insufficient production and/or activity of GFs and their receptors in the diabetic wound healing failure, which ...

Revisiting epidermal growth factor receptor in glioblastoma ...

The EGFR negative cases appear to respond better to therapy, however, the difference is not statistically significant, and EGFR protein expression does not ...

Revisiting epidermal growth factor receptor in glioblastoma multiforme

The present study was designed to evaluate EGFR protein expression in GBM as predictor of response to therapy and survival. Materials and methods: Epidermal ...

Therapeutic Implications of Epidermal Growth Factor Receptor ...

Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer · Department of Internal ...

Epidermal growth factor receptor in non-small cell lung cancer

Epidermal growth factor receptor (EGFR), is one of several somatic ... Revisiting clinical trials using EGFR inhibitor-based regimens in patients ...

Revisiting the IGF-1R as a breast cancer target - Nature

The IRS-1/2 activation was reported in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2 or c-erbB2) positive, and ...