Role for lipid rafts in regulating interleukin|2 receptor signaling

Role for lipid rafts in regulating interleukin-2 receptor signaling

Lipid rafts are plasma membrane microdomains characterized by a unique lipid environment enriched in gangliosides and cholesterol, leading to their ...

Role of lipid rafts in regulating interleukin-2 receptor signaling

Download Citation | Role of lipid rafts in regulating interleukin-2 receptor signaling | Lipid rafts are plasma membrane microdomains characterized by a ...

Lipid rafts and the regulation of IL-2 receptor signalling in T cells ...

Many receptors are constitutively or inducibly localised in rafts, which play a role in co-ordinating the induction of signalling pathways. Results presented in ...

Lipid rafts in immune signalling: current progress and future ...

61 Ubiquitination of FcεRI regulates the strength of IgE signalling. Mono‐ubiquitination of the receptor functions as a signal for endocytosis inside the lipid ...

Docosahexaenoic acid changes lipid composition and interleukin-2 ...

Lipid rafts have been shown to play an important role in the compartmentalization and modulation of cell signaling. We investigated the role of DHA in ...

GPI‐microdomains (membrane rafts) and signaling of the multi ...

Rafts may promote rapid formation of a high affinity IL-2R complex, even at low levels of IL-2 stimulus, and may also form a platform for the ...

Effect of docosahexaenoic acid on interleukin-2 receptor signaling ...

But the molecular mechanisms of immune regulation are not yet elucidated. Lipid rafts are plasma membrane microdomains, in which many receptors localized. The ...

Visualizing Lipid Raft Dynamics and Early Signaling Events during ...

Recent biochemical evidence indicates that an early event in signal transduction by the B-cell antigen receptor (BCR) is its translocation ...

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review

Cytokine receptors are recruited to lipid rafts to mediate cytokine signaling. ... Receptor 2 Internalization and Targeting to the Golgi Are Lipid Raft-Dependent.

The evolving role of lipid rafts and caveolae in G protein‐coupled ...

From a pharmacological perspective, the recognition of signaling microdomains in the membrane – in lipid rafts/caveolae, clathrin-coated pits, ...

Altered lipid raft–associated signaling and ganglioside expression in ...

The organization of signaling molecules into discrete membrane-associated microdomains, called lipid rafts, is vital for regulation of T lymphocyte activation ...

Lipid rafts: signaling and sorting platforms of cells and their roles in ...

Several integral raft receptor proteins that play central roles in the maintenance of a balance between cell proliferation and cell death are ...

Effect of Lipid Rafts on Cb2 Receptor Signaling and 2-Arachidonoyl ...

This growing evidence suggesting that lipid rafts might modulate the endocannabinoid signaling prompted us to investigate also the possible ...

Rafting Down the Metastatic Cascade: The Role of Lipid Rafts in ...

Lipid rafts not only play a role in receptor signaling, but in cancer cell–secreted VEGF as well. Lipid raft–localized Hsp90 was found to stabilize CD24, ...

IL-2 Induces Conformational Changes in Its Preassembled Receptor ...

... Previously we found that IL-2/15 receptors were associated with lipid rafts even in the absence of specific ligands (1), whereas other results suggested ...

The involvement of lipid rafts in the regulation of integrin function

Integrin activity on cells such as T lymphocytes is tightly controlled. Here we demonstrate a key role for lipid rafts in regulating integrin function.

Involvement of lipid rafts in G protein-coupled monoamine receptor ...

These microdomains play important roles in regulating signal transduction and trafficking events. A subgroup of lipid rafts, caveolae, is flask-shaped ...

Role of Death Receptors-associated Lipid Rafts in Oxaliplatin ...

Lipid rafts are cholesterol-enriched, tightly-ordered microdomains of the plasma membrane acting as signaling platforms, and larger rafts contribute to signal ...

Lipid rafts serve as signaling platforms for mGlu1 receptor-mediated ...

We show that the disruption of lipid rafts using methyl-β-cyclodextrin markedly decreased mGlu1α receptor-mediated Ca2+ transients and lipid ...

Lipid raft - Wikipedia

Lipid rafts influence membrane fluidity and membrane protein trafficking, thereby regulating neurotransmission and receptor trafficking.