Role of genetics in inflammatory cardiomyopathy

Role of genetics in inflammatory cardiomyopathy - PubMed

Traditional cardiomyopathy paradigms segregate inflammatory etiologies from those caused by genetic variants. An identified or presumed ...

Some inflammatory cardiomyopathies may be influenced by cardiovascular genetic abnormalities. Identification of a genetic variant has implications for ...

Role of genetics in inflammatory cardiomyopathy - ScienceDirect.com

In this review, we examine the role of genetics in different forms of inflammatory cardiomyopathy, including AM and chronic inflammatory cardiomyopathies.

Genetic testing in inflammatory cardiomyopathy/myocarditis

Definite/moderate gene association with DCM and Arrhythmogenic Cardiomyopathy was based on the ClinGen framework. Variant prioritization was ...

Myocardial Inflammation as a Manifestation of Genetic ...

Consistently with the complex gene-environment interactions underlying the pathophysiology of inflammatory cardiomyopathy [2,6], serum anti-heart autoantibodies ...

Genetics may explain rare heart inflammation in some young people

Gene abnormalities may make some people more susceptible to myocarditis, a rare type of heart inflammation that can affect young people and ...

Genetic Architecture of Acute Myocarditis and the Overlap With ...

Acute myocarditis is an inflammatory condition that may herald the onset of dilated cardiomyopathy (DCM) or arrhythmogenic cardiomyopathy ...

Detecting and Targeting Inflammation in Genetic Cardiomyopathies

Over the past decade, the mechanistic pathways describing how the presence of a pathogenic genetic variant can produce cardiac myocyte damage ...

Myocarditis and inflammatory cardiomyopathy: current evidence and ...

Many questions remain unanswered regarding the pathogenesis of inflammatory cardiomyopathy and the role of the viral infection, the immune ...

Myocarditis: Which Role for Genetics? | Current Cardiology Reports

Myocardial inflammation can result from different infectious and non-infectious causes, including viral or bacterial agents, immunological ...

The diagnostic work up of genetic and inflammatory dilated ...

Unlike hypertrophic cardiomyopathy which is primarily a disease of sarcomeric proteins, the genetic and molecular basis of DCM is more ...

Myocarditis evolving in cardiomyopathy: when genetics and ...

Introduction · 1. Myocarditis is an infectious/inflammatory condition but individual genetic background plays an important role in the ...

Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy

Cardiac inflammation is associated with an earlier disease onset in patients with genetic DCM. This might indicate that myocarditis is an ...

FAQ: Genetic Causes of Myocarditis

Although genetics do not cause myocarditis, inflammation may be influenced by genes ... FAQ on the Role of Genetics in Myocarditis. Written by DeLisa Fairweather ...

Is There a Role for Genetic Testing in Patients With Myocarditis?

In addition, the inflammation induced by the pathogen may trigger the increased genetic susceptibility to develop over DCM or ACM phenotypes.

Genomics in Inflammatory Cardiomyopathies - YouTube

... inflammation as a cause of cardiomyopathy? How is the diagnosis typically made and is there a role for endomyocardial biopsy? Why is genetic ...

Role of genetics in inflammatory cardiomyopathy | Request PDF

... Notably, Castrichini et al. demonstrated that co-existing genetic variants associated with inherited cardiomyopathies, including LMNA, DSP, myosin binding ...

Genetics may explain rare heart inflammation in young people and ...

Gene abnormalities may make some people more susceptible to myocarditis, a rare type of heart inflammation that can affect young people and athletes, a large ...

Familial dilated cardiomyopathy - Genetics - MedlinePlus

Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of ...

Do Genes Influence Susceptibility to Myocarditis? - JACC Journals

For example, mutations in dystrophin increase susceptibility to myocardial CVB3 infection (5). In children with acute myocarditis, the frequency ...