Role of long noncoding RNA in regulating HIV infection

Role of long noncoding RNA in regulating HIV infection—a ...

This review dives into the evolving significance of lncRNAs and their impact on HIV gene expression and viral latency.

Role of long noncoding RNA in regulating HIV infection-a ... - PubMed

We provide an overview of the current knowledge regarding how lncRNAs regulate HIV gene expression, categorizing them as either activators or ...

Role of long noncoding RNA in regulating HIV infection—a ...

However, while we comprehensively understand how host proteins influence HIV gene expression and viral latency, the emerging role of long noncoding RNAs ( ...

Roles of lncRNAs in the transcription regulation of HIV-1

Long noncoding RNAs (LncRNAs) is a class of RNA molecules that are more than 200bp but cannot be translated into proteins. More and more studies have proved ...

Role of long noncoding RNA in regulating HIV infection—a ...

An overview of the current knowledge regarding how lncRNAs regulate HIV gene expression is provided, categorizing them as either activators or inhibitors of ...

Long noncoding RNA NRON contributes to HIV-1 latency ... - Nature

Long noncoding RNAs (lncRNAs) play multiple key regulatory roles in various cellular pathways ... lncRNA functions in HIV-1 latent infection.

Review Roles and potential applications of lncRNAs in HIV infection

By altering the epigenetic landscape at the viral promoter, this HIV-encoded antisense lncRNA is suggested to act as an epigenetic brake to regulate viral ...

Therapeutic Potential of Long Non-Coding RNAs of HIV-1, SARS ...

LncRNAs regulate innate immunity in host–virus interactions. During viral infection, cellular lncRNAs directly regulate viral genes and modify both viral ...

MicroRNAs and long non-coding RNAs during transcriptional ...

Therefore, low levels of MALAT1 may play a role in latency and its induction may promote HIV reactivation [116]. Additionally, lncRNA AK130181 ...

Non-Coding RNAs in HIV Infection, NeuroHIV, and Related ... - MDPI

This review explores the role of various classes of ncRNAs and their regulatory functions implicated in HIV infection, neuropathogenesis, and related ...

The lncRNA NRON modulates HIV-1 replication in a NFAT ... - Nature

A majority of the human genome is transcribed into noncoding RNAs, of which the functions of long noncoding RNAs (lncRNAs) are poorly ...

Long noncoding RNA MALAT1 releases epigenetic silencing of HIV ...

In HIV-1 infected CD4+ T cells, we performed RNA-Sequencing (RNA-Seq) analysis and discovered an up-regulation of MALAT1 (metastasis-associated lung ...

Lnc(ing)RNAs to the “shock and kill” strategy for HIV-1 cure

In this review, we discuss the current state of knowledge of the role of lncRNAs in HIV-1 infection and explore the scope for a lncRNA-mediated genetic ...

Role of long noncoding RNA in regulating HIV infection—a ...

However, while we comprehensively understand how host proteins influence HIV gene expression and viral latency, the emerging role of long ...

Roles of LncRNAs in Viral Infections - Frontiers

Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 ...

The emerging role of long non-coding RNAs in HIV infection

The tightly regulated expression of these lncRNA may enable HIV to achieve synchronized gene expression required for replication success [95] thus leading to a ...

HIV latency and RNA | HIV - Dove Medical Press

Here, we highlight current research on the role of cellular and viral micro RNAs and long non-coding RNAs in the regulation of HIV gene activity ...

Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation ...

Imam et al. (2015) found that NRON regulates HIV-1 transcription in a Nuclear Factor of Activated T cells (NFAT)-dependent manner [54]. NRON has ...

Integrated analysis of lncRNA, miRNA and mRNA profiles reveals ...

Long noncoding RNAs (lncRNAs) can regulate gene expression in a cis-regulatory fashion or as “microRNA sponges”. However, the expression and ...

Identification and characterization of a long non-coding RNA up ...

Saayman, An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription, Mol. ... Emerging role of non-coding RNAs in the course of HIV ...