Role of the Innate Immune Response in Glomerular Disease ...

This review aims to provide an overview of the innate immunity mechanisms involved in podocyte injury and the progression of proteinuric glomerular diseases.

Role of the Innate Immune Response in Glomerular Disease ... - MDPI

Accumulating evidence indicates that inflammatory and immunologic processes play a significant role in the development and progression of glomerular ...

Innate Immunity in the Pathogenesis of Glomerular Disease

Recent studies identify innate immunity as a key player in glomerular disease pathogenesis, and that this involves various immunomodulatory mechanisms.

Role of the Innate Immune Response in Glomerular Disease ...

Accumulating evidence indicates that inflammatory and immunologic processes play a significant role in the development and progression of glomerular ...

The Emerging Role of Innate Immunity in Chronic Kidney Diseases

This review provides an update of both clinical and experimental information, focused on how innate immune signaling contributes to renal fibrogenesis.

(PDF) Role of the Innate Immune Response in Glomerular Disease ...

However, emerging evidence suggests that podocytes not only maintain the glomerular filtration barrier and are important targets of immune ...

The role of innate immunity in diabetic nephropathy and their ...

Therefore, the activation of innate immunity by resident renal and immune cells is critical for initiating and perpetuating inflammation. Toll-like receptors ( ...

Editorial: Innate Immunity in Kidney Injury, Repair and Fibrosis

Innate immunity, a vital system in animals and humans, is precisely regulated, in which a balance between offensive and defensive actions ...

Innate immunity as a driving force in renal disease

Interference with innate immunity has the advantage of controlling both the inflammatory response by the immune system and the responding renal cells. However, ...

Kidney and innate immunity - ScienceDirect.com

The kidney as a vital organ with high energy demand plays a key role in regulating the disease related metabolic process. Increasing research interest has ...

Innate versus adaptive immunity in kidney immunopathology

Innate immunity is the predominant immune response in antigen-independent types of inflammation, such as toxic, ischemic, or traumatic kidney ...

Kidney Disease and Gout: The Role of the Innate Immune System

Hyperuricemia and gout are commonly associated with both acute chronic kidney disease. Common to both conditions is stimulation of the innate immune system.

Glomerulonephritis: immunopathogenesis and immunotherapy

In all autoimmune GN disorders, the central pathogenic elements are loss of tolerance and an adaptive immune response to a self-antigen (Fig.

Mechanisms of immune injury of the glomerulus - UpToDate

Mechanisms of glomerular damage · - Role of the adaptive immune system in glomerulonephritis. Pictures. - Phase-contrast micrograph showing ...

Editorial: Pathogenic aspects of the innate immune system of the ...

First, all three original articles are related to the roles of Mφ in various renal diseases. Mφ is one of the major phagocytic cell components of innate immune ...

Innate Immunity System in Patients With Cardiovascular and Kidney ...

The innate immune system is responsible for rapid, nonspecific responses to any foreign body. Key components of the innate immune system include ...

The innate immune system in human kidney inflammaging

TLR upregulation leads to proinflammatory cytokine induction, fibrosis, and chronic kidney disease progression. TLR2 blockade in a murine model ...

Role of the Innate Immune Response in Glomerular Disease ... - OUCI

Accumulating evidence indicates that inflammatory and immunologic processes play a significant role in the development and progression of glomerular ...

Immunology of Kidney Disease - Annual Reviews

NKT cells, which express both NK and T cell receptors, function as a link between innate and adaptive immunity by sensing lipids presented ...

Innate immunity in diabetic kidney disease - Nature

Immune cells and resident renal cells that activate innate immunity have critical roles in triggering and sustaining inflammation in this setting.