Roles of long noncoding RNAs in human inflammatory diseases

Chemokines, cytokines, and inflammatory cells mediate the onset and progression of many diseases through the induction of an inflammatory ...

Novel long non-coding RNAs associated with inflammation ... - Nature

Emerging studies demonstrate that along with proteins and genomic factors, noncoding RNA are potentially involved in regulation of immune ...

Long non-coding RNAs in diseases related to inflammation and ...

However, the role of lncRNAs in human inflammatory diseases have been paid attention. For examples, the expression of lncRNA Morrbid is significantly up ...

Roles of long noncoding RNAs in human inflammatory diseases

LncRNAs have emerged as important regulators of gene expression and signaling pathways. Increasing evidence suggests that lncRNAs are key ...

Involvement of long noncoding RNAs in the pathogenesis of ...

lncRNAs are involved in abnormal immune regulation and inflammatory responses in autoimmune diseases, which provides new insight into disease pathogenesis.

Non-coding RNAs in human health and disease: potential function ...

Non-coding RNAs (ncRNAs) play increasingly important roles in detecting, developing, and treating all abnormalities related to physiology, pathology, genetics, ...

Role of long non-coding RNA in inflammatory bowel disease

Studies have found that only a small part of the 3 billion base pairs of the human genome has the ability to encode proteins, and the remaining about 98% of RNA ...

The role of long non-coding RNA in Crohn's disease: Heliyon

Current research has demonstrated the involvement of lncRNAs in competitive endogenous RNA, the inflammation process, epithelial barrier function, gut ...

The emerging roles of long non-coding RNA in host immune ...

Cis-lncRNAs because of their co-occurrence with neighboring gene are ideal candidates for investigation of their biological role in host. This is usually based ...

Roles of lncRNAs in NF-κB-Mediated Macrophage Inflammation and ...

Long noncoding RNAs (lncRNAs), which are over 200 bases long but do not code for proteins, play roles in gene expression regulation and signal transduction by ...

Discovery and functional characterization of LncRNAs associated ...

Recent studies from our laboratory revealed that lncRNAs play critical roles in cytokine regulation, inflammation, and metabolism. We demonstrated that lncRNA ...

Role of Long Noncoding RNAs in the Regulation of Cellular Immune ...

4. Role of lncRNAs in Inflammatory Diseases. LncRNAs regulate inflammatory factor expression and inflammatory signaling pathways by interacting ...

Full article: The role of lncRNAs in innate immunity and inflammation

Recently, several lncRNAs were implicated in type I IFN production and ISG activation in professional cells of the innate immune system. In human macrophages, ...

The long noncoding RNA ROCKI regulates inflammatory gene ...

Long noncoding RNAs (lncRNAs) can regulate target gene expression by acting in cis (locally) or in trans (non‐locally). Here, we performed genome‐wide ...

Roles of long noncoding RNAs in human inflammatory diseases

Chemokines, cytokines, and inflammatory cells mediate the onset and progression of many diseases through the induction of an inflammatory response. LncRNAs ...

Involvements of long noncoding RNAs in obesity‐associated ...

Determining the expression and functional role of lncRNAs in mediating obesity-associated chronic inflammation will advance our understanding of ...

significance of long non-coding RNAs in the pathogenesis ...

LncRNAs play important roles in biological processes such as epigenetic modification, transcriptional regulation and post-transcriptional regulation. In this ...

Role of Long Noncoding RNAs in the Regulation of Cellular Immune ...

Under specific physiological conditions, lncRNA expression varies at the cell or tissue level, and lncRNAs can bind to specific miRNAs, target mRNAs, and target ...

"The roles of long noncoding RNAs in inflammation and immune ...

A large number of lncRNAs that are potential regulators of inflammatory response have been identified. In particular, a novel lncRNA, termed as LinfRNA1 (Long ...

Long noncoding RNA identified as a key regulator of inflammation

Called lincRNA-Cox2, it belongs to a recently discovered, highly abundant class of RNAs whose functions are only beginning to be understood. The ...