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SPRTN protease and checkpoint kinase 1 cross|activation loop ...


SPRTN protease and checkpoint kinase 1 cross-activation loop ...

Our data suggest that a SPRTN-CHK1 cross-activation loop plays a part in DNA replication and protection from DNA replication stress.

SPRTN Protease and Checkpoint Kinase 1 Cross-Activation Loop ...

A-SPRTN cells contain about 2-to 3-fold more DPCs than wt cells (Fig. 8b, c). However, ectopic expression of CHK1-wt, but not of kinase ...

SPRTN protease and checkpoint kinase 1 cross-activation loop ...

Kristijan Ramadan's group have published a new paper which shows how cells keep the DNA replication machinery moving when faced with ...

SPRTN protease and checkpoint kinase 1 cross-activation loop ...

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Search results. Found 10471 matches for. Share. Kristijan Ramadan's ...

SPRTN protease and checkpoint kinase 1 cross-activation loop ...

The SPRTN metalloprotease is essential for DNA-protein crosslink (DPC) repair and DNA replication in vertebrate cells. Cells deficient in SPRTN protease ...

A model of DNA damage response activation at stalled replication ...

... loop of CHK1-SPRTN activation. The previously ... SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

Mechanisms and Regulation of DNA-Protein Crosslink Repair ...

SPRTN Protease and Checkpoint Kinase 1 Cross-Activation Loop Safeguards DNA Replication. Nat. Commun. 10 (1), 3142. doi:10.1038/s41467-019-11095-y. PubMed ...

SPRTN cleaves CHK1 and releases kinase-active CHK1 fragments ...

... Checkpoint Kinase 1 and Repair | ResearchGate, the professional ... SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

SPRTN-dependent DPC degradation precedes repair of damaged ...

K. et al. . SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication . Nat. Commun. 2019. ;. 10. : 3142 . Google ...

The protease SPRTN and SUMOylation coordinate DNA-protein ...

Wiseman, et al. SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat. Commun., 10 (2019), p. 3142.

The Trinity of SPRTN Protease Regulation - Cell Press

... protein crosslink proteolysis repair ... SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

SPRTN protease-cleaved MRE11 decreases DNA repair and ...

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat. Commun. 10, 3142 (2019). Article PubMed PubMed ...

SPRTN protease and checkpoint kinase 1 cross-activation loop ...

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication // Nature communications, 10 (2019), 1; 1-18. doi: 10.1038/s41467 ...

USP11 mediates repair of DNA–protein cross-links by ...

33. Halder, S. ∙ Torrecilla, I. ∙ Burkhalter, M.D. ... SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

SPRTN-dependent DPC degradation precedes repair of damaged ...

(2019). SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat. Commun., 10, 3142. 18. Perry,M ...

Cdc48/p97 segregase: Spotlight on DNA-protein crosslinks

... SPRTN and CHK1 (checkpoint kinase 1). Replication-associated ... SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by ...

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat Commun. 2019;10(1):3142. Article PubMed PubMed ...

SPRTN and TDP1/TDP2 Independently Suppress 5-Aza-2

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat. Commun. 2019, 10 (1), 3142, DOI: 10.1038 ...

sprtn - ZFIN Gene

SprT-like domain-containing protein Spartan. UniProtKB:A0A0G2L7I0 · InterPro. 1 - 1 of 1 ... (2019) SPRTN protease and checkpoint kinase 1 cross-activation loop ...

SPRTN protease and SUMOylation coordinate DNA-protein ... - OUCI

DPC modification by SUMO-1 favours SPRTN proteolysis as the preferred pathway for DPC repair. ... SPRTN protease and checkpoint kinase 1 cross-activation loop ...