- Scaling cell culture processes🔍
- Principles of Mammalian Cell Culture Process Scale‑up🔍
- Cell Culture Process Scale|Up Challenges for Commercial|Scale ...🔍
- Scale|Up Technologies for the Manufacture of Adherent Cells🔍
- Things to Know & Consider Before Scaling Up Cell Cultures🔍
- Scale|up analysis for a CHO cell culture process in large ...🔍
- Cell Culture Scaling🔍
- Exploring Principles of Bioreactor Scale|Up🔍
Scaling cell culture processes
Scaling cell culture processes - Automata
The scale up of cell culturing can be achieved by increasing the volumes of the culture process and by improving the efficiency through lab automation.
Principles of Mammalian Cell Culture Process Scale‑up - BDO USA
The approach involves evaluating and optimizing bioreactor scaling parameters, process control, and gassing strategies.
Cell Culture Process Scale-Up Challenges for Commercial-Scale ...
As stated previously, the mixing environment of a bioreactor will have a major effect on the biological performance of PSC aggregates. Spherical ...
Scale-Up Technologies for the Manufacture of Adherent Cells
Scale-up systems progressively increase the surface area/culture volume as the cell number raises (28). Scale-out systems are based on the use of multiple ...
Things to Know & Consider Before Scaling Up Cell Cultures
Scaling up cell culture involves transitioning from small laboratory-scale cultures to larger production scales. This process is not without its challenges.
Scale-up analysis for a CHO cell culture process in large ... - PubMed
Bioprocess scale-up is a fundamental component of process development in the biotechnology industry. When scaling up a mammalian cell ...
Cell Culture Scaling - Aber Instruments
Scaling is an important aspect with respect to any cell culture process which involves transferring a bioprocess from one bioreactor size to another.
Exploring Principles of Bioreactor Scale-Up - BioProcess International
Cell-culture process development involves investigation of both scale-dependent and scale-independent bioreactor parameters. Scale-independent ...
How to Scale Out and Scale Up Cell Therapy Production
One reason for this is that suspension cultures can be grown in conventional, large-scale stirred-tank bioreactors, which reduces the number of processing steps ...
Cell Culture Scale-Up Using Stirred-Tank Single-Use Bioreactors
The Scale Up Assist software (Figure 4) feature from Eppendorf simplifies this process. The software is auto-populated with the power numbers ...
Intensification of large-scale cell culture processes - ScienceDirect
This short review is focused on starting the fed-batch at high seeding densities, reducing the duration of the fed-batch as an efficient strategy to increase ...
Current Challenges with Cell Culture Scale-up for Biologics ...
Most delays nowadays tend to occur during transfer from process development scale (10 mL–5 L) to the larger bioreactors because that part of the ...
Alternative High-Yield Cell Culture Systems - Sigma-Aldrich
At this scale cells are usually grown in T-flasks ranging from 25cm2 to 175cm2. Typical cell yields from a T175 flask range from 1x107 for an attached line to ...
Preparing for cell culture scale-out: establishing parity of bioreactor
Cell-based therapies have the potential to become treatment options for many diseases, but efficient scale-out of these therapies has proven to ...
Scaling Stirred-Tank Bioreactors for Cell Culture Processes
P/V and VVM are the most widely used methods for developing scale-up and scale-down models of cell culture operations in stirred-tank bioreactors.
Scale-up Benchtop Cell Cultures Using HYPER Technology - Corning
Much has been written about scaling up cell culture for bioprocessing and other applications that require a very high density of cells.
Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot ...
... cell-culture-bioprocess-scale-up-workflow-bench-pilot-production-scale ... During scale-up, process performance optimized at small scale needs ...
Scaling Up Your Cell cultures to Bioreactors | Biocompare
“It is important that throughout scale-up the same environment is created for the cell culture,” he says. “This is realized by having the same ...
Chapter 12 Laboratory Scaleup of Cell Cultures (0.5-50 Liters)
With the modern tools of molecular and cell biology, many researchers find the need to scale-up cell culture to produce large quantities of cells or conditioned ...
A Look into Biologic Scale-Up Strategies - BioPharm International
Scale-up strategies for cell culture will require a deep understanding of overall bioprocess workflows. ... Optimizing cell-culture processes for ...