Selective and cross|reactive SARS|CoV|2 T cell epitopes in ...

Selective and cross-reactive SARS-CoV-2 T cell epitopes ... - PubMed

Many unknowns exist about human immune responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus.

Selective and cross-reactive SARS-CoV-2 T cell epitopes ... - Science

We demonstrate a range of preexisting memory CD4 + T cells that are cross-reactive with comparable affinity to SARS-CoV-2 and the common cold coronaviruses.

Selective and cross-reactive SARS-CoV-2 T cell epitopes in ...

We provide direct evidence that numerous CD4+ T cells that react to SARS-CoV-2 epitopes actually cross-react with corresponding homologous sequences from any of ...

Selective and cross-reactive SARS-CoV-2 T cell epitopes ... - Science

SARS-CoV-2–reactive T cells were expanded, with one pool of peptides spanning the en- tire sequence of the spike protein (CD4-S) and the other a ...

Cross-reactive memory T cells associate with protection against ...

Mateus, J. et al. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science 370, 89–94 (2020).

Review SARS-CoV-2 human T cell epitopes - ScienceDirect.com

This remarkable breadth of epitope repertoire has implications for vaccine design, cross-reactivity, and immune escape by SARS-CoV-2 variants. Previous article ...

[PDF] Selective and cross-reactive SARS-CoV-2 T cell epitopes in ...

A range of preexisting memory CD4+ T cells that are cross-reactive with comparable affinity to SARS-CoV-2 and the common cold coronaviruses ...

T cell response to intact SARS-CoV-2 includes coronavirus cross ...

We were interested in benchmarking peptide-based estimates for SARS-CoV-2 to the levels of reactivity to whole viral antigen and, in comparing epitope ...

Immunogenic T cell epitopes of SARS-CoV-2 are recognized by ...

Our results, based on specific tetramer binding, provide evidence supporting the presence of frequent cross-reactive CD8 T cells to SARS-CoV-2 antigens in non- ...

Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell ...

We studied T cell responses to SARS-CoV-2 and HCoVs in convalescent COVID-19 donors and identified a highly conserved SARS-CoV-2 sequence, S 811-831.

Targets and cross-reactivity of human T cell recognition of common ...

... to predict T cell cross-reactivity. Previous ... Phillips, et al. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

Nonconserved epitopes dominate reverse preexisting T cell ... - Nature

CD8 T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses. ... cross-reactive ...

SARS-CoV-2 human T cell epitopes: Adaptive immune response ...

This remarkable breadth of epitope repertoire has implications for vaccine design, cross-reactivity, and immune escape by SARS-CoV-2 variants.

Mapping and role of T cell response in SARS-CoV-2–infected mice

... T cell responses after SARS-CoV-2 infection ... , et al. 2020 . Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

Profiling the SARS-CoV-2-specific T-cell response - The Lancet

Mateus, J ∙ Grifoni, A ∙ Tarke, A ∙ et al. Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science. 2020; 370:89-94.

Selective and cross-reactive SARS-CoV-2 T cell epitopes in ... - OUCI

Preexisting immune response to SARS-CoV-2 Robust T cell responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus occur in most ...

Selective and cross-reactive SARS-CoV-2 T cell ... - H1 Connect

This excellent study by Mateus et al. analyzes human blood samples derived from 2019 and demonstrates 142 T cell epitopes that show cross-reactivity with SARS- ...

Immune Epitopes of SARS-CoV-2 Spike Protein and Considerations ...

E. Phillips. , et al. 2020 . Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans . Science. 370. : 89. –. 94 . Google Scholar · Crossref.

Selective and cross-reactive SARS-CoV-2 T cell epitopes ... - Matilda

Matilda - Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

Cross-reactivity of SARS-CoV-2– and influenza A–specific T cells in ...

We, therefore, analyzed whether exposure to influenza A virus (IAV) antigens could influence the T cell repertoire in response to SARS-CoV-2.