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Selenoproteins in brain development and function


Selenoproteins in brain development and function - PubMed

Expression of selenoproteins is widespread in neurons of the central nervous system. There is continuous evidence presented over decades that low levels of ...

Selenoproteins in brain development and function - ScienceDirect.com

Selenoproteins are essential for mammalian brain development and function. Mouse models help to understand the functions of selenoproteins in the brain.

Selenoproteins in brain development and function - ScienceDirect

Selenoproteins are essential for mammalian brain development and function. •. Mouse models help to understand the functions of selenoproteins in the brain.

Selenoproteins in Nervous System Development and Function - PMC

Selenoproteins are a distinct class of proteins that are characterized by the co-translational incorporation of selenium (Se) in the form of the 21 st amino ...

The role of selenoproteins in neurodevelopment and neurological ...

When selenium is deprived from the diets of four generations of mice, an increased brain uptake of selenium was identified (Kuhbacher et al., 2009), suggesting ...

Roles of Selenoproteins in Brain Function and the Potential ...

Ca2+ Homeostasis and ER Stress. Seven ER-resident selenoproteins are involved mainly in regulating calcium flux, protein folding, and redox balance in the ER.

The role of selenoproteins in neurodevelopment and neurological ...

Selenium and selenoproteins play a role in many biological functions, particularly in brain development and function. This review outlines the role of each ...

Selenium and selenoprotein function in brain disorders - Pillai - 2014

Selenoproteins are important for normal brain function, and decreased function of selenoproteins can lead to impaired cognitive function and ...

Selenoprotein P concentrations and risk of progression from mild ...

There is a growing literature investigating the effects of selenium on the central nervous system and cognitive function.

Selenium, selenoproteins and brain function - SpringerLink

Still, available evidence already suggests that selenoproteins are playing important roles for brain development, function, and disease in mice - and also most ...

Selenoproteins in brain development and function | Request PDF

In particular selenoprotein P is central to brain function by virtue of its selenium transport function into and within the brain. We summarize which ...

Selenium and Selenoproteins in Brain Development, Function, and ...

Its influence is mediated primarily through selenoproteins, a class of proteins characterized by the co-translational incorporation of Se as the amino acid ...

Selenium, selenoproteins and neurodegenerative diseases

The apparent neuroprotective role of Se supplementation in the brain is not only directly associated with antioxidant effects of organic and ...

(PDF) Editorial: Selenium and Selenoproteins in Brain Development ...

Development, Function, and Disease. Front. Neurosci. 15:821140. ... host of additional Se-related proteins involved in selenoprotein biosynthesis ...

Selenium and Selenoproteins in Health - MDPI

Selenium supplements promote neuronal activities and brain functions by increasing SELENOP, GPX4, and SELENOW levels in brain. Selenium deficiency can lead to ...

Neuronal selenoprotein expression is required for interneuron ...

The epileptic phenotype of Sepp-deficient mice suggests that a moderate reduction of brain Se content suffices to impair brain function. We can ...

The Role and Mechanism of Essential Selenoproteins for Homeostasis

Selenoproteins are important for normal brain function, and a decline in their function can lead to impaired cognitive function and neurological ...

CHAPTER 27: Selenoproteins in Brain - RSC Books

An essential role for selenoproteins in brain function was not evident until recently. Mainly through studies in mice genetically made ...

Editorial: Selenium and Selenoproteins in Brain Development ...

Humans with rare mutations in selenoprotein biosynthesis genes exhibit neurological defects that parallel those detailed in knockout mice, ...

Selenoproteins in Nervous System Development and Function - OUCI

Selenoproteins in Nervous System Development and Function. https://doi.org ... role of thioredoxin reductases in brain development. PLoS One 3:e1813