Self|Assembly of Switchable Protein Nanocages via ...

Self-Assembly of Switchable Protein Nanocages via Allosteric Effect

This strategy highlights that the precise self-assembly of coat protein only relies on allosterically driven protein–ligand interactions rather than ...

Self-Assembly of Switchable Protein Nanocages via Allosteric Effect

Request PDF | On Oct 27, 2020, Miaomiao Xu and others published Self-Assembly of Switchable Protein Nanocages via Allosteric Effect | Find, read and cite ...

Self-Assembly of Switchable Protein Nanocages via Allosteric Effect

Protein cages have promising applications in highly efficient gene transportation. Many methods of engineering protein–interface ...

Development of Self-Assembled Protein Nanocage Spatially ...

We previously reported that the structure of antigens in nanoparticles is critical for humoral immune response, and solvent-mediated assembly of ...

Self-assembled nanoreactors based on peptides and proteins

Peptide-based amphiphile fibers with catalytic activity are created via simple mixed assembly. •. Close proximity of catalytic groups as well as hydrophobic ...

Engineering Self-Assembling Protein Nanoparticles for Therapeutic ...

(2001) reported an early example of a self-assembling protein nanoparticle constructed using ... assembly; mosaics generated using this method are anticipated to ...

Nanocaged Platforms: Modification, Drug Delivery and Nanotoxicity ...

studied self-assembly of VP6, a rotavirus capsid protein that could be used ... via a coordination-directed self-assembly processes. 5-5-4 ...

Shape‐Anisotropic Assembly of Protein Nanocages with Identical ...

... self-assembly of protein architectures. Unlike other noncovalent ... protein arrays through discrete nanocages as intermediates (Figure 1).

Protein nanocage engineering for Pickering emulsions and potential ...

For example, milk is used to deliver nutrients via the gastrointestinal tract (GIT) of mammals' progeniture [3]. Emulsions are a mix of two immiscible liquids ...

Self-assembly and regulation of protein cages from pre-organised ...

Geometric protein assemblies and polyhedral protein cages have been built using orthogonal interacting CC units. Coiled-coil protein origami ( ...

Engineering Self-Assembling Protein Nanoparticles for Therapeutic ...

(100,101) The main considerations in protein nanoparticle manufacturing are the dose, protein production, nanoparticle assembly, and ...

Engineering protein nanocages as carriers for biomedical applications

Recent studies have taken the efforts to a higher level by creating self-assembling protein structures through de novo design. The assembly of ...

Manufacturing of non-viral protein nanocages for biotechnological ...

Protein nanocages can be defined as highly ordered, nano-scale architectures. In general, they are produced through the self-assembly of multiple monomers ...

(a) Schematic illustration of the formation of protein nanocages by...

[9] Through the addition of a chaperone analogue we can selectively switch off the self-assembly of each of these segments individually, resulting in ...

Protein assembly: Controllable design strategies and applications in ...

... proteins in a targeted manner to drive protein self-assembly. ... (2) Stability of protein assembly: the complex spatial structures formed via ...

Assembly of Protein Cages for Drug Delivery - MDPI

Target-switchable Gd(III)-DOTA/protein cage nanoparticle ... nanoparticles camouflaged using self-proteins: Overcoming immune recognition.

A prototype protein nanocage minimized from carboxysomes with ...

Protein nanocages (PNCs), which are widely found in the biosphere, are well-organized structures formed through self-assembly. They provide ...

Investigating Designed Protein Nanocages as a Modular Platform ...

... assembly, and show preliminary results from target-triggered disassembly experiments. In the fourth chapter, I aim to develop ... using protein nanocages.

Protein nanocage architectures for the delivery of therapeutic proteins

Biomedical utility of self-activities of PNCs and delivery of enzyme-like activities as therapeutics using PNCs. (a) Dps loaded with Mn(II) ions (MnDps) is with ...

Triggered reversible disassembly of an engineered protein nanocage

proteins which specifically interact with the interior of the protein shell during self-assembly.16,20,21. 37. This native feature has been ...