Sex and gender affect immune aging

Sex and gender affect immune aging - PubMed

The proposed review aims to elucidate the intricate interplay between biological factors (sex differences) and socially constructed factors ...

Sex and gender affect immune aging - Frontiers

This work seeks to offer a comprehensive understanding of why men and women may experience divergent trajectories in immune aging and varying outcomes in terms ...

How sex and age affect immune responses, susceptibility to ...

It is well known that the aging process affects sexual dimorphism regarding immunocompetence and disease susceptibility. Aging women lose their immunological ...

Sexual-dimorphism in human immune system aging - Nature

Unexpectedly, genomic differences between sexes increase after age 65, with men having higher innate and pro-inflammatory activity and lower ...

Effects of sex and aging on the immune cell landscape as assessed ...

Using small conditional RNA sequencing, we found that females had a lower percentage of natural killer (NK) cells and a higher percentage of ...

Immune system changes with age differ between men and women

How does sex affect the immune system? ... In the new study, they uncovered important sex differences in immune system aging. A particularly ...

Sex differences in immune responses | Nature Reviews Immunology

In birds, females exhibit higher antibody and cell-mediated immune responses to immune challenges, and these effects are often most pronounced ...

(PDF) Sex and gender affect immune aging - ResearchGate

Besides sex hormones, sex chromosomes play a role, as several immune genes are found on the X chromosomes. ... ... X-chromosome inactivation ...

The Confluence of Sex Hormones and Aging on Immunity - Frontiers

Sex steroids affect immune function by binding to specific hormone receptors expressed in diverse immune cells (155). With age, the hormonal milieu of females ...

Sex, the aging immune system, and chronic disease - ScienceDirect

In particular, females are generally more prone to autoimmunity, but experience lower rates of infections and chronic inflammatory disease. Sex hormones, genes ...

Sex differences in biological aging with a focus on human studies

In general, women live longer than men, consistent with lower biological ages as assessed by molecular biomarkers, but there is a paradox. Women ...

During aging, the decline of sex hormones is accompanied by a gradual functional decline of the immune system, which is particularly evident in females. Again, ...

Sex, gender and immunosenescence: a key to ... - Immunity & Ageing

Gender and sex are known to be associated with longevity. While males are usually stronger, females live longer. In the Western world, ...

Sex and Gender Impact Immune Responses to Vaccines Among the ...

Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence ...

The influence of sex and gender on immunity, infection and ... - ISS

Sex/gender significantly contribute to shape the immune responses, contributing to dif- ferences in the pathogenesis of infectious diseases in males and females ...

Immune system and COVID-19 by sex differences and age

Females have a higher innate immune response than males. •. Females produce lower levels of inflammatory mediators and increase the production ...

The intersection of biological sex and gender in adverse events ...

These data support a larger role for biological sex than for gender in the occurrence of AE following influenza vaccination in older adults and ...

Gender-Specific Impact of Sex Hormones on the Immune System

The immune system protects the body against infections similarly in men and women, although women display stronger innate and adaptive immune responses than men ...

Sex Differences in Immune System Aging and Responsiveness to ...

The research mission of the laboratory is to uncover age-related changes in the immune system that negatively affect health outcomes of older individuals.

Sex and Age Differences in Immunity to Influenza SCORE

The overarching hypothesis: Female-biased vaccine-induced immunity to influenza viruses is age-dependent and reflects both hormonal and genetic differences ...