Sex bias in immune response

Sex differences in immune responses | Nature Reviews Immunology

Generally, adult females mount stronger innate and adaptive immune responses than males. This results in faster clearance of pathogens and ...

Sex bias in immune response: it is time to include the sex variable in ...

Females generally mount stronger immune response than males and are much more susceptible to autoimmune rheumatic diseases.

Immune Cells Have Sex and So Should Journal Articles - PMC

Generally, females mount higher innate and adaptive immune responses than males, which can result in faster clearance of pathogens but also contributes to ...

Sex bias in lymphocytes: Implications for autoimmune diseases

Autoimmune diseases are characterized by a significant sex dimorphism, with women showing increased susceptibility to disease.

Considering how biological sex impacts immune responses and ...

Biological sex affects innate and adaptive immune responses to self and foreign antigens, resulting in sex differences in autoimmunity as well ...

Sex-biased adaptive immune regulation in cancer development and ...

Whereas females have a more responsive immune system, they are also more susceptible to excessive inflammation and autoimmune diseases, such as lupus and ...

Sex Bias and Autoimmune Diseases - ScienceDirect.com

Although sex bias in immune function has long been documented, the mechanism by which this occurs and the evolutionary advantage of the sex bias are still ...

Sex Hormones Determine Immune Response - Frontiers

Immune responses to environmental factors like infections and vaccinations are also sex-biased (18). Women maintain a high immune reactivity post-viral ...

Sex differences in immune function and disease risk are not easily ...

In humans, fewer pathogens and lower parity in urban, industrialized environments has been suggested to leave female immune systems under- ...

Sex differences in CD8 + T cell responses during adaptive immunity

Sex bias is a hallmark of autoimmune diseases and cancer (Fish, 2008; Klein & Flanagan, 2016). ... Compared to males, females mount a more ...

Sex differences in innate and adaptive immunity impact fetal ...

Pregnancies carrying female fetuses have a more regulatory immune response, whereas pregnancies carrying male fetuses have a stronger inflammatory response.

Sex bias in MHC I-associated shaping of the adaptive immune system

Abstract. HLA associations, T cell receptor (TCR) repertoire bias, and sex bias have independently been shown for many diseases. While some ...

Immune Sexual Dimorphism: Connecting the Dots | Physiology

This sex bias may also be explained by the stronger female immune response, which leads to higher inflammation levels in females, but it is not clear why ...

The conneXion between sex and immune responses

There are notable sex-based differences in immune responses to pathogens and self-antigens, with female individuals exhibiting increased susceptibility to ...

The influence of sex and gender on immunity, infection and ... - ISS

Sex bias in neuroscience and bio- medical research. Neurosci Biobehav Rev ... Regulation of the immune response by sex hormones. I. In vitro effects of.

In immune cells, X marks the spot(s) | Whitehead Institute

Examples include the typically weaker male immune response to pathogens and vaccines, and the female-biased frequency of autoimmune diseases.

Sex-biased Immune Responses Following SARS-CoV-2 Infection

Spotlight. Sex-biased Immune Responses Following SARS-CoV-2 Infection ... Males are disproportionately affected by severe disease and death from severe acute ...

The X in seX-biased immunity and autoimmune rheumatic disease

Here, we summarize sex differences in immune composition and function and review recent work supporting a role for the X chromosome in the pathogenesis of sex- ...

Sexual dimorphism in immune function and oxidative physiology ...

We conclude that sex-bias in immunity in birds (when present) is most likely skewed toward females, corresponding to patterns found in mammals.

[PDF] Sex differences in immune responses - Semantic Scholar

It is emphasized that sex is a biological variable that should be considered in immunological studies and contribute to variations in the incidence of ...

Autoimmune disease in women

Autoimmunity refers to a pathological immune response of the body's immune system against itself. Autoimmune disease is widely recognized to be significantly more common in women than in men, and often presents differently between the sexes.