Sex differences contribute to age|related inflammation

Sex differences contribute to age-related inflammation: Study

Older female mice had more immune cells entering areas of the body where they shouldn't according to a new study, demonstrating that sex ...

In women during reproductive age, estrogen inhibits NK cell cytotoxicity during the ovulatory phase (Giefing-Kroll et al., 2015). NK cells in postmenopausal ...

Sex Differences in the Inflammatory Profile in the Brain of Young and ...

IL-12/IL-23p40, CCL13, and IL-10 were increased in females compared to males but not with age. These results indicate that there are sex ...

Sex and gender affect immune aging - Frontiers

Starting from the sixth decade of life, the human immune system undergoes significant age-related changes that progressively lead to a state known as ...

Sexual-dimorphism in human immune system aging - Nature

Unexpectedly, genomic differences between sexes increase after age 65, with men having higher innate and pro-inflammatory activity and lower ...

Sex differences in markers of oxidation and inflammation ...

Males and females differ in oxidative and inflammatory stress mechanisms. Males display a higher production of ROS and less efficient antioxidant mechanisms.

Sex Differences in Age Trajectories of Physiological Dysregulation

Women show higher mean levels of inflammatory markers and overall burden but slower rates of increase in inflammation with age. This suggests ...

Sex Differences in the Inflammatory Profile in the Brain of Young and ...

IL-12/IL-23p40, CCL13, and IL-10 were increased in females compared to males but not with age. These results indicate that there are sex differences in cortical ...

Sex differences in immune responses | Nature Reviews Immunology

Puberty. The multiple effects of sex steroids on immune cells play a prominent role in sex differences in inflammatory status during puberty.

Sex Differences in Poststroke Inflammation: a Focus on Microglia ...

These data suggest that the predisposition of pro-inflammatory signaling observed in young males is compensated by age in females, possibly via ...

Age and Sex Influence the Neuro-inflammatory Response ... - Frontiers

Aged female brain showed a higher pro-inflammatory response to LPS compared to adult female and to aged male, as revealed by ex vivo binding to TSPO receptors ...

Sex differences in systemic inflammation and immune function in ...

Females had lower systemic inflammation compared with males in response to DIO intervention and a higher proportion of macrophage (M)2-like ...

Sex Differences in Inflammation and Muscle Wasting in Aging and ...

When assessing age-related strength loss, the abrupt age-related decline measured (KES) occurs earlier in women than men, whereas the corresponding isometric ...

Estrogen contributes to the sex difference in the occurrence of ...

In addition, our results suggest that estrogen plays a role in visceral adipose tissue inflammation, particularly by regulating the appearance ...

Accelerated resolution of inflammation underlies sex differences in ...

Krishnaraj S. Rathod, Vikas Kapil, Shanti Velmurugan, Rayomand S. Khambata, Umme Siddique, Saima Khan, Sven Van Eijl, Lorna C. Gee, ...

Sex differences in the pro-inflammatory cytokine response to ...

Clinical observations have provided compelling evidence that humoral and cell-mediated immune responses markedly differ across sexes, with women ...

Acute inflammatory profiles differ with sex and age after spinal cord ...

Despite a changing demographic towards older age at the time of SCI, the effects of sex or age on inflammation remain to be elucidated. This ...

Estrogen contributes to the sex difference in the occurrence of ...

Estrogen contributes to the sex difference in the occurrence of senescence-related T cells during the development of visceral adipose tissue inflammation.

Sex differences matter in the gut: effect on mucosal immune ...

Sex differences also manifest in the prevalence of gut associated inflammatory and autoimmune disorders, including Crohn's disease, ulcerative ...

... Inflammation poses a genuine threat to both the speed of the aging progression and the development of age-related conditions (Franceschi et al. 2018).