Silencing of ST6Gal I enhances colorectal cancer metastasis by ...

Aberrant sialylation has long been correlated with human cancer. Increased ST6 Gal I (β-galactoside α 2, 6 sialyltransferase) and ...

These findings indicate that gene silencing of ST6Gal I could enhance metastasis of CRC by down-regulating KAI1 activity and rescuing its negative effects on ...

Silencing of ST6Gal I enhances colorectal cancer metastasis by ...

Silencing of ST6Gal I enhances colorectal cancer metastasis by down-regulating KAI1 via exosome- mediated exportation and thereby rescues ...

[PDF] Silencing of ST6Gal I enhances colorectal cancer metastasis ...

Silencing of ST6Gal I enhances colorectal cancer metastasis by down-regulating KAI1 via exosome-mediated exportation and thereby rescues integrin signaling.

ST6Gal1: Oncogenic signaling pathways and targets - PMC

ST6Gal1-mediated hypersialylation of β1 integrin in colon cancer cells also resulted in enhanced fibronectin binding that promoted survival via ...

Recent advances in the development of sialyltransferase inhibitors ...

ST6Gal I plays various roles in colon cancer (Table 6). A study has shown that S ST6Gal I enhances colorectal cancer metastasis by down-regulating KAI1, a ...

Insights into the role of sialylation in cancer progression and ...

Furthermore, hypersialylation promotes tumour metastasis via several routes, including stimulating tumour invasion and migration through ...

The Distinct Roles of Sialyltransferases in Cancer Biology and Onco ...

However, ST6GalNAc6 may also enhance the metastatic capability of tumor cells, as silencing ... Silencing of ST6Gal I Enhances Colorectal Cancer Metastasis by ...

Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical ...

We showed that down-regulation of ST6Gal-I promoted cell apoptosis and inhibited proliferation and invasion in cervical cancer cells. Knockdown ...

ST6Gal-I overexpression facilitates prostate cancer progression via ...

Here, we proved that ST6Gal-I silencing significantly attenuates PCa cell proliferation, migration and invasion capability. As mentioned ...

Carcinogenesis - Content Listing - Medscape

Silencing of ST6Gal I enhances colorectal cancer metastasis by down-regulating KAI1 via exosome-mediated exportation and thereby rescues integrin signaling.

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ...

Previously, we determined that PDAC cells with high ST6Gal-I expression had reduced gemcitabine-mediated cell death (15); however, the mechanism underlying this ...

Clinical Correlations of a2,6-Sialyltransferase Expression in ...

metastases: Metastatic potential of B16 melanoma ... Silencing of ST6Gal I enhances colorectal cancer metastasis by down-regulating KAI1 via exosome-mediated.

α2,6 Sialylation mediated by ST6GAL1 promotes glioblastoma growth

Swindall AF, Bellis SL. Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma ...

Sialyltransferase Inhibitors for the Treatment of Cancer Metastasis

In the study, ST8Sia-I expression negatively correlated with miR-33a/let-7e expression. Colorectal cancer cells with overexpressed ST8Sia-I have enhanced ...

Recent advances in the development of sialyltransferase inhibitors ...

Jung, Silencing of ST6Gal I enhances colorectal cancer metastasis by down ... Colorectal Cancer Metastases, CANCER Res, № vol. 52, с. 1775; Klohs ...

Expression of β 1 integrins. ( A ) Upper panels: mock-transfected ...

Silencing of ST6Gal I enhances colorectal cancer metastasis by down ... These findings indicate that gene silencing of ST6Gal I could enhance metastasis of CRC ...

Silencing of long non-coding RNA ANRIL inhibits the development ...

Knockdown of ANRIL promotes gastric cancer cell apoptosis in vitro ... We next examined the effect of ANRIL expression on the apoptosis of GC ...

Browsing OpenAccess@KRIBB - Open Access@KRIBB

Silencing of ST6Gal I enhances colorectal cancer metastasis by down ... Carcinogenesis, vol. 37, no. 11, pp. 1089-1097Y R Jung; J J Park; Yeung Bae Jin ...

Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer ...

Similarly, SOX2 was silencing impaired sphere formation of activin/HGF-treated colorectal cancers. Overexpression of SOX2 rescued the stem cell- ...