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Single|cell expression noise and gene|body methylation in ...


Single-cell expression noise and gene-body methylation in ... - Nature

Gene-body methylation (gbM) refers to an increased level of methylated cytosines specifically in a CG sequence context within genes.

Single-cell expression noise and gene-body methylation ... - PubMed

Gene-body methylation (gbM) refers to an increased level of methylated cytosines specifically in a CG sequence context within genes. gbM is found in plant ...

[PDF] Single-cell expression noise and gene-body methylation in ...

It is found that gbM genes have lower expression noise levels than unmethylated genes, and it is observed that fewer RNAseq reads map to introns of gBM ...

Single-cell expression noise and gene-body - ProQuest

Gene-body methylation (gbM) refers to an increased level of methylated cytosines specifically in a CG sequence context within genes.

Gene body methylation buffers noise in gene expression in plants

In this study, we found a link between gene body methylation and noise in gene expression in Arabidopsis thaliana. More specifically, genes with ...

Single-cell expression noise and gene-body methylation in ...

We find that gbM genes have lower expression noise levels than unmethylated genes. However, an analysis of covariance revealed that, if other ...

Effect of DNA methylation on gene transcription is associated ... - NCBI

Through this, gene body methylation may effectively inhibit 'transcriptional noise', meaning that gene expression levels between cells may vary despite the same ...

Analyzing single-cell bisulfite sequencing data with MethSCAn

As DNA methylation affects gene expression, DMRs can provide insights into the unique epigenetic and gene regulatory characteristics of cell ...

Effect of genomic and cellular environments on gene expression noise

Since the early single-cell studies showing the variability of gene expression in isogenic populations [25], many individual chromatin and ...

Gene Body Methylation Confers Transcription Robustness in ...

... noise of highly expressed genes in Stylophora ... Single-cell expression noise and gene-body methylation in Arabidopsis thaliana.

Gene Body Methylation in Plants: Mechanisms, Functions, and ...

Single-cell expression noise and gene-body methylation in Arabidopsis thaliana ... Phylogenetic shifts in gene body methylation correlate with gene expression ...

Single-cell expression noise and gene-body methylation in ... - OUCI

Single-cell expression noise and gene-body methylation in Arabidopsis thaliana ; Journal: Heredity, 2019, № 2, p. 81-91 ; Publisher: Springer Science and Business ...

DNA methylation and transcriptional noise - Epigenetics & Chromatin

A long-standing hypothesis posits that gene body methylation reduces transcriptional noise associated with spurious transcription of genes.

DNA methylation correlates with transcriptional noise in response to ...

Functional annotation of genes with changes in transcript-level expression or containing DML revealed several enriched biological processes potentially involved ...

The sound of silence: Transgene silencing in mammalian cell ...

Transgene silencing: loss or downregulation of expression of a transgene in a cell despite its encoding DNA remaining present in the cell's ...

Single-cell expression noise and gene-body methylation in ... - CoLab

Here, we therefore tested whether gbM was associated with reduced expression noise in Arabidopsis thaliana, using single-cell transcriptome sequencing data from ...

Methylation entropy landscape of Chinese long‐lived individuals ...

In this study, we constructed high-resolution blood epigenetic noise landscapes for this cohort by a methylation entropy (ME) method using whole ...

Independent regulation of gene expression level and noise ... - PLOS

Single-cell mRNA-seq was performed in human preimplantation embryos [33], which provides us with the opportunity to investigate gene expression noise in human.

Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells

Cell populations can be strikingly heterogeneous, composed of multiple cellular states, each exhibiting stochastic noise in its gene expression.

Gene body methylation buffers noise in gene expression in plants

In this study, we found a link between gene body methylation and noise in gene expression inArabidopsis thaliana. More specifically, genes with high levels of ...