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Single|cell multi|omics and lineage tracing to dissect cell fate ...


Single-cell multi-omics and lineage tracing to dissect cell fate ...

The concept of cell fate relates to the future identity of a cell, and its daughters, which is obtained via cell differentiation and ...

Single-cell multi-omics and lineage tracing to dissect cell fate ...

The concept of cell fate relates to the future identity of a cell, and its daughters, which is obtained via cell differentiation and division.

Multiomic single-cell lineage tracing to dissect fate-specific gene ...

With CellTag-multi, we present a novel approach for independently profiling lineage barcodes with single-cell chromatin accessibility without ...

Multiomic single-cell lineage tracing to dissect fate-specific gene ...

To adapt scLT for chromatin accessibility capture, we have developed 'CellTag-multi.' 57. CellTag-multi is based on our previous CellTagging ...

(PDF) Single-cell multi-omics and lineage tracing to dissect cell fate ...

Using lineage-traced single-cell data, we demonstrate that scDiffEq offers improved reconstruction of held-out cell states and prediction of cell fate from ...

[PDF] Single-cell multi-omics and lineage tracing to dissect cell fate ...

Semantic Scholar extracted view of "Single-cell multi-omics and lineage tracing to dissect cell fate decision-making" by L. Haghverdi et al.

Single-cell lineage capture across genomic modalities with CellTag ...

a, A framework for relating early cell state with fate using single-cell lineage tracing. ... 3: Application of CellTag-multi to dissect clonal ...

(PDF) Multiomic single-cell lineage tracing to dissect fate-specific ...

We validate CellTag-multi in mouse hematopoiesis, characterizing transcriptional and epigenomic lineage priming across progenitor cell populations. In direct ...

Single-cell multi-omics and lineage tracing to dissect cell fate ... - OUCI

Single-cell multi-omics and lineage tracing to dissect cell fate decision-making. https://doi.org/10.1016/j.stemcr.2022.12.003 ·. Journal: Stem Cell Reports ...

The technological landscape and applications of single-cell multi ...

We highlight the impact that single-cell multi-omics technologies have had in cell lineage tracing, tissue-specific and cell-specific atlas ...

Connecting past and present: single-cell lineage tracing

Recent advances in single-cell transcriptomics hold great promises to elucidate the molecular mechanisms of cell fate determination of animal ...

Single-cell multi-omics and lineage tracing to dissect cell fate ...

Understanding, predicting, and manipulating cell fate has been a long-sought goal of developmental and regenerative biology. Recent insights obtained from ...

Single-Cell Transcriptomics Meets Lineage Tracing

Although single-cell transcriptomics provides detailed phenotypic information, the predicted lineage trajectories do not necessarily reflect genetic ...

Single-Cell Transcriptomics Meets Lineage Tracing - ScienceDirect

First a phylogenetic tree is constructed based on genetic labels identified in single cells. This tree can then be refined using transcriptomics ...

Lineage tracing meets single-cell omics: opportunities and challenges

Progress in modern lineage-tracing methods that combine genetic lineage analysis with omics-based characterization of cell states ...

scLTdb: a comprehensive single-cell lineage tracing database

The emergence of scLT has begun to reveal the gene regulatory program of cell fate decision in various tissues, such as central nervous system ...

Single-cell multi-omics and lineage tracing to dissect cell fate ...

Single-cell multi-omics and lineage tracing to dissect cell fate decision-making. STEM CELL REPORTS (2023). Overview; Write a Review. Get Full Text · Add to ...

Single-Cell Transcriptomics Meets Lineage Tracing

Since lineage recon- struction based on single-cell transcriptomics is independent from the true genetic relationship between cells, we reserve.

Bartomeu Colom on X: "'Single-cell multi-omics and lineage tracing ...

'Single-cell multi-omics and lineage tracing to dissect cell fate decision-making' https://t.co/n3TaU36MlT.

Single-cell lineage tracing with endogenous markers

Resolving lineage relationships between cells in an organism provides key insights into the fate of individual cells and drives a ...