Single|cell transcriptomic profiles in the pathophysiology within the ...

Single-cell transcriptomic profiles in the pathophysiology within the ...

Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease, resulting in a huge socio-economic impact.

Single-cell transcriptomic profiles in the pathophysiology within the ...

These data identified the hub genes involved in pathophysiologic changes within the microenvironment of early DKD.

Single-cell transcriptomic analysis highlights origin and pathological ...

Here we use single-cell RNA sequencing to profile cells from normal endometrium, atypical endometrial hyperplasia, and endometrioid endometrial ...

Single-cell transcriptomic profiles in the pathophysiology within the ...

Advanced single-cell RNA sequencing (scRNA-seq) could reveal the complex architecture and interaction with the microenvironment in early DKD. We used scRNA-seq ...

Integration of Pan-Cancer Cell Line and Single-Cell Transcriptomic ...

A versatile method that infers cell-level drug response in scRNA-seq data facilitates the development of therapeutic strategies to target ...

Cell and transcriptomic diversity of infrapatellar fat pad during knee ...

Results We identified multiple subclusters of fibroblasts, macrophages, adipocytes and endothelial cells with unique transcriptomic profiles.

Single-cell transcriptomic analysis uncovers heterogeneity in the ...

Single-cell RNA sequencing (scRNA-seq) was performed on 32,337 cells of labial glands from three pSS patients and three healthy individuals. We analyzed all ...

Single-cell transcriptomic and proteomic analysis of Parkinson's ...

Moreover, the relative contributions of neuronal versus glial cell populations to PD pathophysiology remain unknown. Single-cell and nucleus RNA ...

Single-cell transcriptomics: A new tool for studying diabetic kidney ...

The comprehensive understanding of single-cell transcriptomics through single-cell RNA-seq and single-nucleus RNA-seq will provide us new insights into the ...

Single-cell transcriptomics reveals skewed cellular ... - JCI Insight

These immune cells are an integral part of the normal PA niche, and their presence and balanced composition are likely a part of vascular ...

Single‐Cell RNA Sequencing and Spatial Transcriptomics Reveal ...

This study integrates single-cell RNA sequencing and spatial transcriptomics to comprehensively characterize the composition and alterations ...

A single–cell type transcriptomics map of human tissues - Science

The analysis highlights distinct expression clusters corresponding to cell types sharing similar functions, both within the same organs and ...

Single-Cell RNA Sequencing Profiles Identify Important ... - Frontiers

Objective: Single-cell RNA sequencing (scRNA-seq) analyses have provided a novel insight into cell-specific gene expression changes in diseases.

A comparative analysis of single-cell transcriptomic technologies in ...

These single cells are then RNA sequenced to identify the different cell types and study the gene expression profiles in each cell [16]. Single-cell ...

Decoding the pathogenesis of spermatogenic failure in ... - Cell Press

Single-cell transcriptome profiling of testes from patients with cryptorchidism. Individual testicular cells were isolated from three adult ...

Transcriptomic, epigenomic, and spatial metabolomic cell profiling ...

We find that the same cell type, including thin limb, thick ascending limb loop of Henle and principal cells, display distinct transcriptomic, chromatin ...

Current Status and Prospects of the Single-Cell Sequencing ... - MDPI

Single-cell RNA sequencing (scRNA-seq) is a method that focuses on the analysis of gene expression profile in individual cells.

A practical guide to single-cell RNA-sequencing for biomedical ...

Consistent with this, a consortium of biomedical researchers has recently committed to employ scRNA-seq for creating a transcriptomic atlas of ...

Shoot and root single cell sequencing reveals tissue

Most available scRNAseq studies do not indicate an exact time point of harvest although it is well established that the transcriptome changes significantly ...

Single-cell analysis to understand the diversity of immune cell types ...

Single-cell next-generation sequencing assays are powerful tools to understand the nature of the immune cells that drive disease pathogenesis.